Pirfenidone Tablets

Pirfenidone

Therapeutic classification: Antifibrotic agent

What is pirfenidone?

It is a prescription medicine.

It is used to treat idiopathic pulmonary fibrosis.

Pirfenidone is available as Pirfekast 400.

Pirfekast 400 is a generic formulation of pirfenidone, manufactured by Aprazer Healthcare.

Aprazer Healthcare is a pharmaceutical manufacturer and exporter.

We are a recognized generic drug supplier.

We supply drugs to Asia, Africa, and America.

Our product portfolio comprises a comprehensive range of drugs.

• Antiviral drugs
• Antifibrotic drugs
• Antibiotics
• Anticancer drugs

The pirfenidone tablet is used for:

Idiopathic pulmonary fibrosis -It helps prevent further scarring of the lungs.

Pirfenidone tablet side effects-

• Diarrhea
• Nausea
• Skin reactions
• Indigestion
• Fatigue
• Headache

The serious side effects that require medical attention:

• Liver damage
• Severe skin reaction
• Allergic reaction

How does the pirfenidone tablet work?

Its exact mechanism is not established.

As an anti-inflammatory agent and antifibrotic, it slows down lung scarring.

Precautions to be followed while on pirfenidone therapy:

Direct sun exposure must be reduced as the drug may increase risk of photosensitivity.

Using pirfenidone in patients with renal dysfunction must be monitored for kidney function.

Patients with end-stage renal disease are advised to avoid pirfenidone.

The following drugs may interact with pirfenidone:

Fluvoxamine and Ciprofloxacin may increase drug exposure.

It must be cautiously combined with other drugs (hepatotoxic drugs).

Rifampicin may reduce levels of pirfenidone in the blood.

Warnings associated with the use of pirfenidone:

Its use must be avoided in individuals with a previous allergy to the drug.

Pirfenidone therapy must be followed by liver monitoring, as the drug damages the liver.

Its use in hepatic and renal dysfunction needs careful organ monitoring.