Anti-Diabetic Combination

Antidiabetic Combination

Antidiabetic drugs are used to lower the high glycemic index.

It renders effective glucose control.

Diabetes is a condition in which-

• • The body is not able to produce insulin.
• • It is not able to utilize insulin.

The body is not able to process glucose. It causes its accumulation in the blood.

The Complications Caused by Excessive Sugar

The high blood sugar levels lead to several short-term and long-term effects.

Diabetic Ketoacidosis

It is caused by to lack of insulin.

It is usually in type-1 diabetics.

It is a condition in which glucose is not digested for energy.

The body starts utilizing fats. It leads to the production of toxins (ketones).

Dehydration

It is a condition with very high levels of blood sugar.

It occurs in people with type 2 diabetes.

The body is not able to utilize glucose.

The excess glucose is excreted through the kidneys.

It causes severe dehydration.

The Long–term Complications Include

The chronic rise in blood sugar levels for several years leads to –

• • Irreversible organ or tissue damage.
• • Consistent high sugar levels in the blood lead to nerve damage.

Heart Diseases – High blood sugar thickens the blood flow.

It causes narrowing of the arteries.

It interrupts the blood flow.

It increases the risk of a heart attack.

Nerve Damage – High sugar levels lead to poor flow. It damages blood vessels.

It inhibits the supply to nerves. It causes nerve damage.

Kidney Damage – It causes narrowing of blood vessels in the kidney.

The kidney is unable to filter blood. The toxins are accumulated in the body.

Eye Damage – It blocks the nerve supply to the eye. It damages blood vessels in the retina.

The blood vessels swell up. It leads to leakage of the fluid.

Foot Issues – The circulation of the blood is halted.

The poor blood flow to the limbs. It leads ulcers.

It also increases the risk of infection in limbs.

A severe condition can lead to amputation.

Weak Immune System - It lowers immunity. It interferes with WBC functioning.

It increases the risk of infection.

Skin and Oral Conditions – It damages tiny vessels. It interrupts blood flow.

It increases the risk of-

• • Fungal infections
• • Gum diseases
• • Tooth decay

Mental Health Issues - They damage blood vessels and nerves in the brain.

It impairs cognitive functions.

It leads to –

• • Mood swings
• • Anxiety
• • brain fog

Antidiabetic Combination Drugs Are Working

The antidiabetic drug combination significantly reduces the blood sugar levels.

They offer synergistic effects.

They have multitargeted effects.

They control blood glucose in multiple ways-

• • They increase insulin sensitivity.
• • The sulphonyl urea- It increases insulin production.
• • The biguanides – They reduce glucose formation.
• • Alpha-glucosidase inhibitors – They reduce glucose breakdown.
• • SGLT2 inhibitors – They increase excess glucose excretion through urine.

The Types of Antidiabetic Drugs

• • Biguanides
• • Sulphonylureas
• • Thiazolidinediones
• • SGLT2 enzyme inhibitors
• • DPP-4 inhibitors
• • Meglitinides
• • Alpha-glucosidase inhibitors
• • Bile acid sequestrants
• • Dopamine-2 agonists

The Best Antidiabetic Combinations

The common antidiabetic combination includes –

• • Metformin with DPP-4 inhibitors
• • Metformin with SGLT2 inhibitors

Why Use an Antidiabetic Combination?

• • It offers potent glucose control
• • It reduces cardiovascular side effects.
• • It has lowered renal side effects.
• • It has long-term efficacy.
• • It reduces frequent dosing.

Aprazer Healthcare’s Leadership in Antidiabetic Drug Manufacturing

Aprazer Healthcare is the top antidiabetic drug manufacturer.

We manufacture the widest range of affordable generic anti-diabetic drugs.

Manufacturing the global quality antidiabetic drugs, we are the top exporters to countries worldwide.

Our exclusive range of products includes-

• • Saxagliptin + Metformin tablets
• • Linagliptin + Metformin tablets

We are the leading antidiabetic drug exporters and suppliers.

We supply bulk antidiabetic medicines to the leading hospitals, government institutions, and dispensaries.