Anti-allergic & Leukotriene Receptor Antagonist

Montelukast & Levocetirizine Tablets

Aprazer Healthcare – Leading WHO-GMP certified manufacturer and global exporter of Montelukast & Levocetirizine Tablets (Montiaxis L). High-quality, reliable, affordable medicine.

Formulation Tablets
Standard WHO-GMP Certified Quality
Supply Type Global Export & Institutional Supply
Finished Commercial Brand

Available finished formulation under our brand name MONTIAXIS L.

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WHO-GMP Certified
Global Export Ready
Quality Assured

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Comprehensive Medical Overview

Montelukast & Levocetirizine Tablets

Classification: Anti-allergic & Leukotriene Receptor Antagonist

About Montelukast & Levocetirizine Tablets

A dual combination of Levocetirizine (second-generation antihistamine) and Montelukast (leukotriene receptor antagonist), prescribed for allergic rhinitis, chronic urticaria, and relief of seasonal allergy and asthma symptoms.

Montelukast & Levocetirizine Tablets (Montiaxis L) Manufactured by Aprazer Healthcare

Montiaxis L is formulated and manufactured under strict WHO-GMP compliance, delivering proven bioequivalence, therapeutic efficacy, and clinical reliability globally.

Montelukast & Levocetirizine

Classification: Dual Anti-Allergic & Leukotriene Receptor Antagonist

What is the Montelukast–Levocetirizine Combination?

It is a dual-action oral medication combining an H1-receptor antihistamine (Levocetirizine) and a cysteinyl leukotriene receptor antagonist (Montelukast) to treat allergic rhinitis, persistent congestion, and urticaria.

Montiaxis L (montelukast–levocetirizine), manufactured by Aprazer Healthcare, provides comprehensive dual-action relief across upper and lower respiratory allergic pathways.

Aprazer Healthcare – Global Quality in Respiratory & Allergy Care

Aprazer Healthcare is a WHO-GMP certified manufacturer and exporter delivering high-grade anti-allergic formulations across Asia, Africa, and the Americas.

Indications & Uses

  • Allergic rhinitis: Relieves seasonal hay fever and year-round perennial allergic rhinitis, mitigating sneezing, runny nose, and nasal congestion.
  • Comorbid asthma and allergy: Assists in long-term combined management of allergic airway inflammation and bronchial hyperresponsiveness.
  • Chronic urticaria: Effectively relieves allergic skin hives, pruritus, and erythema.
  • Exercise-induced bronchoconstriction: Helps prevent acute airway narrowing provoked by exercise in patients with allergic asthma.

Mechanism of Action

• Montelukast blocks the cysteinyl leukotriene CysLT1 receptor in airways, preventing smooth muscle contraction, vascular permeability, and excessive mucus secretion.

• Levocetirizine selectively blocks peripheral histamine H1-receptors, rapidly alleviating sneezing, itchy/watery eyes, and rhinorrhea.

Precautions & Side Effects

  • Drowsiness: Levocetirizine can cause mild sedation; evening administration before bed is strongly recommended.
  • Neuropsychiatric monitoring: Montelukast has an FDA alert for mood changes, agitation, sleep disturbances, and depression; report any mood changes immediately.
  • Not for acute asthma attacks: This combination is not a rescue inhaler; it does not relieve acute bronchospasm.
  • Allergy skin tests: Must be discontinued several days prior to scheduled allergy prick tests.

FAQ

Why should montelukast-levocetirizine be taken at bedtime?

Levocetirizine can cause mild drowsiness and fatigue. Taking the medication at night ensures peak allergy coverage while resting and minimizes daytime sleepiness.

Can one use montelukast-levocetirizine during a sudden asthma attack?

No. Montelukast-levocetirizine is a maintenance medication for chronic prevention and long-term control. An acute asthma attack requires a fast-acting rescue bronchodilator inhaler (such as albuterol).

Why shouldn't the medication be discontinued abruptly?

Abrupt discontinuation can cause a rapid resurgence of severe allergic rhinitis or rebound itching and hives. Discuss gradual tapering with your healthcare provider.

Can it be used in patients with glaucoma?

While second-generation antihistamines carry a much lower anticholinergic risk than first-generation drugs, patients with narrow-angle glaucoma should consult an ophthalmologist before use.

Can montelukast-levocetirizine lead to dry eyes or blurred vision?

Yes. Mild anticholinergic effects of antihistamines may occasionally cause temporary eye dryness or slight visual blurring.