NSAIDs Combinations
Non-Steroidal Anti-Inflammatory Drug (NSAID) combinations combine potent analgesic and anti-inflammatory compounds with muscle relaxants or gastroprotective agents. They are designed to alleviate acute and chronic pain, reduce swelling, and manage musculoskeletal conditions while optimizing patient comfort.
| S.No. | Dosage Form | Composition | Action |
|---|---|---|---|
| 189 | Tablets | Aceclofenac 100 mg + Diacerein 50 mg | |
| 190 | Tablets | Aceclofenac 100 mg + Paracetamol 325 mg + Thiocolchicoside 4/8 mg | |
| 191 | Tablets | Aceclofenac 100 mg + Paracetamol 325 mg + Trypsin Chymotrypsin 50,000/1,50,000 units | |
| 192 | Tablets | Aceclofenac 100 mg + Thiocolchicoside 4/8 mg | |
| 193 | Tablets | Aceclofenac 100 mg + Drotaverine HCL 80 mg | |
| 194 | Tablets | Baclofen 10/25 mg | |
| 195 | Capsules | Celecoxib 100/200 mg | |
| 196 | Tablets | Dexketoprofen 25 mg + Thiocolchicoside 4 mg | |
| 197 | Tablets | Dexketoprofen 25 mg + Paracetamol 325 mg | |
| 198 | Tablets | Diclofenac Sodium 50 mg + Thiocolchicoside 4/8 mg | |
| 199 | Tablets | Etodolac 300 mg | |
| 200 | Tablets | Etodolac 300/400 mg + Thiocolchicoside 4 mg | |
| 201 | Tablets | Etoricoxib 60/90/120 mg | |
| 202 | Tablets | Etoricoxib 60/90 mg + Paracetamol 325 mg | |
| 203 | Tablets | Etoricoxib 60 mg + Thiocolchicoside 4/8 mg | |
| 204 | Tablets | Etoricoxib 60 mg + Tolperisone 150 mg | |
| 205 | Capsules | Flupirtine Maleate 100 mg | |
| 206 | Tablets | Flupirtine Maleate 100 mg | |
| 207 | Tablets | Ibuprofen 400/600 mg + Thiocolchicoside 4 mg | |
| 208 | Tablets | Ketoprofen 50/100 mg + Thiocolchicoside 4/8 mg | |
| 209 | Tablets | Ketoprofen 100 mg | |
| 210 | Tablets | Lornoxicam 4/8 mg + Thiocolchicoside 4/8 mg | |
| 211 | Tablets | Lornoxicam 4/8/16 mg | |
| 212 | Tablets | Lornoxicam 4/8 mg + Paracetamol 325 mg | |
| 213 | Tablets | Meloxicam 15/30 mg | |
| 214 | Tablets | Naproxen 250/500/550 mg | |
| 215 | Tablets | Naproxen 250/500 mg + Domperidone 10 mg | |
| 216 | Tablets | Sumatriptan 25/50/100 mg | |
| 217 | Tablets | Sumatriptan 50/85 mg + Naproxen 275/500 mg | |
| 218 | Capsules | Thiocolchicoside 4/8 mg | |
| 219 | Tablets | Thiocolchicoside 4/8 mg | |
| 220 | Tablets | Thiocolchicoside 4 mg + Diclofenac Potassium 50 mg | |
| 221 | Tablets | Tolperisone 150 mg + Etodolac 400 mg | |
| 222 | Tablets | Trypsin 48/96 mg + Bromelain 90/180 mg + Rutoside Trihydrate 100/200 mg | |
| 223 | Tablets | Trypsin 48 mg + Bromelain 90 mg + Rutoside Trihydrate 100 mg + Aceclofenac 100 mg | |
| 224 | Tablets | Trypsin 48 mg + Bromelain 90 mg + Rutoside Trihydrate 100 mg + Diclofenac Potassium 50 mg | |
| 225 | Tablets | Trypsin 48 mg + Bromelain 90 mg + Rutoside Trihydrate 100 mg + Diclofenac Sodium 50 mg | |
| 226 | Tablets | Trypsin-Chymotrypsin 50,000 units + Bromelain 90 mg + Rutoside Trihydrate 100 mg | |
| 227 | Tablets | Trypsin Chymotrypsin 1,00,000/2,00,000 units |
NSAID Combinations
These are the non-steroidal drug molecules.
These are the drugs that relieve inflammation.
It is used to treat pain, swelling.
The Uses of NSAIDs
It relieves pain and swelling.
- • Arthritis
- • Muscle aches
- • Back pain
- • Period pain
- • Dental pain
- • Fever
- • Gout
- • Post-operative pain
- • Clot prevention
The Working of NSAIDs
It blocks the prostaglandins. The prostaglandins cause –
- • Nerve pain.
- • Reduces inflammation.
- • Dilation of blood vessels.
- • Leads to increased temperature
The Types of NSAIDs
Non-selective NSAIDs- They inhibit the two -
COX-1 and COX-2 enzymes.
These drugs inhibit prostaglandin synthesis.
It lowers the pain.
It reduces inflammation.
Examples-
- • Ibuprofen
- • Naproxen
- • Diclofenac
Selective NSAIDs-
These are the COX-2 inhibitors.
It inhibits pain and inflammation.
They do not have GIT side effects.
Examples -
- • Meloxicam
- • Indomethacin
- • Piroxicam
Common Side-effects of NSAIDs
The long-term use of NSAIDs increases the risk of GIT bleeding.
It includes GIT side-effects-
- • Indigestion
- • Stomach pain and cramps
- • Stomach ulcers
Cardiovascular disease risk-
- • Heart failure
- • Blood clots
Kidney side-effects - Fluid retention
Why Use NSAIDs Combinations?
The NSAIDs are widely used in combination to-
- • It offers more potent control over pain.
- • It offers a lower dosing of a single drug.
- • It reduces the frequency of doses.
- • It reduces the need for opioid drugs.
The Commonly Used NSAIDs Combinations
The NSAIDs are combined with other drug classes-
Acetaminophen – It is an anti-inflammatory drug. It has more efficient pain control.
Spasmolytic Agents – They relax the smooth muscles in the intestine and uterus.
Opioids – They are added to relieve severe pain during trauma or an accident.
Proton Pump Inhibitors – These relieve GIT side-effects.
Muscle Relaxants – They reduce skeletal muscle spasm. It reduces inflammation and pain.
Antihistaminics – They are added as an adjuvant to NSAIDs to induce sleep or control allergic reactions.
Aprazer Healthcare – The Leader in the NSAIDs Drug Market
Aprazer Healthcare manufactures a wide variety of NSAIDs and their combinations.
Equipped with modern manufacturing infrastructure.
We manufacture top-quality NSAID combinations that are highly effective and affordable.
We are a global NSAID exporters from India.
Supplying standards-driven pharmaceutical products globally, Aprazer Healthcare is an export-focused NSAIDs supplier to Africa, Southeast Asia.
Our Product Portfolio Consists of Top-quality Nsaids Combinations
Etodolac + Thiocolchicoside Tablets - They relieve pain and muscle spasm. It is widely used in muscle strains.
Etoricoxib and Paracetamol Tablets – They relieve arthritis pain.
Trypsin + Bromelain + Rutoside Trihydrate - It is used to treat inflammation, swelling, and pain.
It is widely used for –
- • Arthritis pain
- • Muscle pain
- • Back pain
- • Post-surgery pain
- • Trauma
Conclusion
NSAIDs are widely used as over-the-counter drugs. These are used for headache, muscle pain, and toothache, etc.
It should be used cautiously to prevent the –
- • Risk of cardiovascular problems
- • Kidney damage.
They show potential drug interactions. They should be used cautiously with other drugs.
FAQ
A Widely Used Drug for Dental Pain. Which is It?
• Ketoprofen 100 mg tablets
• Ketoprofen 50/100 mg + Thiocolchicoside 4/8 mg tablets
Does Long–term NSAIDs Use Cause Kidney Damage?
Increases the risk of kidney damage.
NSAIDs Trigger Asthma. How?
• Anti-inflammatory agent.
• It reduces allergic reactions.
What Are the Serious Side Effects of NSAIDs?
• Gastrointestinal bleeding
• Stomach pain
• IBS
The Top Quality NSAIDs Used for Migraine?
Sumatriptan 25/50/100 mg tablets.