Description
Lapakast -250 mg
Composition: Lapatinib Ditosylate IP -250mg
Therapeutic Class: Antineoplastic
What is Lapakast?
Lapakast is an anti cancer medicine that is used orally against solid tumors and breast cancers.
Uses of Lapakast –
- • Advanced-stage Breast cancer
- • Metastatic Breast Cancer
- • Lung cancer
How does Lapakast work?
- • It causes programmed cell death by inhibiting HER-2 and EGFR receptors.
- • It inhibits signals for cancer cell growth and division.
Common side-effects
- • Anorexia
- • Diarrhea
- • Skin rashes, itchiness
- • Stomatitis, constipation, and abdominal pain
- • Palmar-plantar erythrodysaesthesia
- • Pain in the extremity, back pain
- • Hair loss
Serious side-effects
- • Bleeding in the stomach
- • Dehydration
- • Electrolyte imbalance
- • QT prolongation
- • Hand and foot syndrome
Toxicities
- • Cardiac toxicities
- • Hepatotoxicity
- • Interstitial Lung Disease
- • Pneumonitis
Contraindications
Not to be used in patients –
- • Hypersensitive or allergic to the drug or its excipients.
- • Breastfeeding mothers
- • Pregnant women
Precautions
To be used cautiously in patients with
- • Heart disease
- • Low blood count
- • Liver disease
Warnings
To be used under medical supervision
Important Safety and Monitoring Information
Regular monitoring is crucial for patient safety and treatment efficacy –
- • The liver function – AST, ALT, bilirubin, alkaline phosphatase
- • Cardiac function – periodic assessment of left ventricular ejection
- • Electrolyte balance – potassium, magnesium levels
- • GIT disturbances – hydration status
- • Regular blood count – Complete blood count
FAQ
Frequently Asked Questions
Does Lapakast (lapatinib) therapy cause hair loss?
It causes mild hair thinning.
Alcohol, while on Lapakast (lapatinib) therapy, is not safe. Why?
It may cause liver toxicity.
Avoid tooth extractions while on Lapakast (lapatinib) therapy. Why?
It delays healing and may cause bleeding.
Can one use antacids with Lapakast (lapatinib)?
It reduces the absorption.
Take it at a gap.
What are the serious risks with Lapakast (lapatinib)?
- Liver damage
- Heart problem
- Lung inflammation
Can Lapakast (lapatinib) cause ocular side effects?
It alters the tear production.
It causes-
- Itching
- Burning
- Watery eyes
Why avoid direct sun while on Lapakast (lapatinib) therapy?
It increases sensitivity.
It elevates the risk of sunburns.
Which is the affordable brand for cancer drugs?
Aprazer Healthcare is an anti-cancer drug manufacturer.
