Lopikast
Lopinavir and Ritonavir USP Tablets 200mg/50mg
Lopikast
Composition: Lopinavir – 200 mg, Ritonavir – 50 mg
Classification: HIV Medicine
Lopikast: Powerful Inhibition, Proven HIV Control
Lopikast is prescribed widely and stands out due to its potent viral suppression.
Aprazer Healthcare – Advancing HIV Therapy with Global Quality Standards
- • World-class Manufacturing Facility – Lased with advanced technology and precise quality monitoring.
- • Backed with Scientific innovation and continuous R&D for new drug development.
- • Global compliance, trusted worldwide – WHO-GMP certified
- • Affordable HIV Medicines
- • Available in 50+ countries
What is Lopikast?
A fixed-dose combination, widely used against HIV infection.
Lopinavir induces viral cell death, and ritonavir prolongs its effect.
Uses of Lopikast
- • HIV infection
How does Lopikast work?
It inhibits the HIV protease enzyme.
Inhibits cell multiplication and replication.
Causes viral cell death.
Benefits
- • Significantly lowers the viral load
- • Improves immune function
- • Increases CD-4 cell count
Common Side Effects
- • Nausea
- • Vomiting
- • Tiredness
- • Increased cholesterol levels
- • Increased blood sugar
- • Headache
- • Rash, itchiness
Serious Side Effects
- • Hepatotoxicity – elevated liver enzymes
- • QT prolongation
- • Severe heart complications
- • Lactic acid buildup
- • Pancreatitis
- • Allergic reaction
- • Wasting of face, buffalo hump, thinning of legs
Precautions
To be used cautiously in:
- • Severe liver disorders
- • Renal impairment
- • Cardiovascular diseases
- • High cholesterol levels
- • Pancreatitis
- • Bleeding disorders
- • Elderly and children
- • Pregnant and breastfeeding women
Important Monitoring Considerations
- • Liver functions
- • Kidney functions
- • Blood sugar and blood pressure
- • Signs of pancreatitis
Drug Interactions
Dose adjustment may be required when used with:
- • Anticonvulsant drugs
- • Cardiovascular drugs
- • Antihypertensives
- • Antifungal and anti-tubercular drugs
- • Cholesterol-lowering medicines – statins
- • Herbal formulations – ergotamine derivatives
- • Sedatives
Contraindications
- • Severe liver dysfunction
- • Hypersensitivity or allergic reaction to the drug or its excipients
Warnings
To be used under medical prescription.
Do not discontinue abruptly in Hepatitis B patients – may cause serious liver flare-ups.
FAQ
Frequently Asked Questions
Lopikast (Lopinavir, Ritonavir) in diabetes. Is it safe?
It increases sugar levels.
Regular monitoring of sugar is required.
Lopikast (Lopinavir, Ritonavir) can affect contraception. How?
It reduces the absorption of birth control pills.
Do not feed the child while on Lopikast (Lopinavir, Ritonavir) therapy. Why?
It can pass into the breast milk.
Lopikast (Lopinavir, Ritonavir) long use effect. What is it?
It leads to fat redistribution.
One may lose fat from the face, arms, and legs.
Fat accumulates in the-
- Abdomen
- Upper back
- Breast
Lopikast (Lopinavir, Ritonavir) causes lipid changes. How?
It leads to an increase in
- Cholesterol
- Triglyceride
Alcohol and Lopikast (Lopinavir, Ritonavir) therapy. Is it unsafe?
It increases the risk of-
- Liver toxicity
- Pancreatitis
Which is the HIV medicine manufacturer in India?
Aprazer Healthcare is the pharmaceutical manufacturer.
