Mitomycin
Composition: Mitomycin – 10 mg
Classification: Antineoplastic
Proven Efficacy, Global Acceptance
Mitomycin, driven out of proven scientific formula, is widely accepted by world-leading oncologists for affordable and effective anti cancer medicine used against several cancers.
Aprazer: A Trusted Name in Oncology
Aprazer healthcare is the leading name in oncology, manufacturing world-standard anti cancer medicines.
The leading oncology exporter that develops affordable advanced care therapeutics.
It supplies to 50 + countries.
WHO-GMP certified, assured therapeutic efficacy and safety.
What is Mitomycin?
Mitomycin is an anticancer medicine used to treat various cancers.
It is used alone or in combination as a chemotherapy agent .
Uses of Mitomycin
- • Gastrointestinal cancers
- • Blood cancer
- • Breast cancer
- • Pancreatic cancer
- • Cancers of the uterus (urinary bladder)
How does it work?
Mitomycin causes cancer cell death by cross-linking DNA strands, inhibiting DNA replication, and multiplication.
Common Side Effects
- • Nausea
- • Mouth ulcers
- • Low blood count
- • Risk of infections
- • Diarrhea
- • Loss of appetite
- • Weakness
- • Local tissue necrosis
Serious Side Effects
- • Pulmonary fibrosis – dry cough, shortness of breath
- • Renal toxicity – increased creatinine, proteinuria
- • Hepatic toxicity
- • Hemolytic uremic syndrome
Precautions
To be cautiously used in:
- • Renal disorders
- • Hepatic disorders
- • People with pulmonary fibrosis or pneumonitis
- • Elderly patients
- • Avoid combining with other myelosuppressant drugs
- • Bleeding disorders
- • Severe infections
Contraindications
- • Not to be used if any previous allergy or hypersensitivity to Mitomycin or any excipients.
- • Breastfeeding mothers
- • Pregnant women
Warning
To be used under the supervision of a medical practitioner or oncology specialist, having adequate diagnostic and monitoring facilities.
Important Safety and Monitoring Information
Monitor the following regularly:
- • Total blood count
- • Renal functions
- • Pulmonary functions
- • Hepatic functions
Storage
It should be stored at 2-8 degrees Celsius, protected from light.
Administration Instructions
- • To be administered as a slow IV infusion.
- • Avoid IV push or rapid bolus.
- • To be used immediately after reconstitution.
FAQ
Frequently Asked Questions
Which is the affordable brand for Mitomycin injection?
Mitomycin 10mg, manufactured by Aprazer Healthcare.
How is Mitomycin injection administered?
It is given as –
Intravenous infusion
Intravesical instillation
It can turn the urine blue/violet. Why?
It temporarily changes the colour due to the drug colour.
What functions are monitored with Mitomycin therapy?
- Blood functions
- Liver functions
- Kidney functions
- Lung functions
- Bladder functions for bladder instillation
Can alcohol be used while on Mitomycin therapy?
It may increase strain on the liver.
What are the serious signs to be monitored with Mitomycin therapy?
- High fever
- Unusual bleeding
- Decreased urination
- Shortness of breath
- Swelling in the ankles/legs
- Irregular heartbeat
- Chest pain
Avoid pregnancy while on Mitomycin therapy?
It can harm the fetus.
Can Mitomycin affect your skin /hairs?
It can cause temporary hair loss.
It causes skin pigmentation.
It increases sun sensitivity.
Why Aprazer Healthcare is the trusted name in oncology?
Aprazer Healthcare is the oncology injectable manufacturer.
