NAB PACLIKAST 100

paclitaxel Injection 100mg/vial (lyophilized)

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Description

NAB PACLIKAST-100

Composition:

  • • Paclitaxel IP 100 mg
  • • Human Albumin IP (after reconstitution) – 900 mg

Therapeutic Class: Antineoplastic

What is Nab Paclikast?

It is an anti cancer medicine, formed of two drugs, Paclitaxel and human albumin.
It is used against multiple cancers.

Uses of Nab Paclikast –

It is widely used for –

  • • Advanced-stage breast cancer
  • • Pancreatic cancers
  • • Lung cancers (non-small)

How Nab Paclikast work?

  • • Paclitaxel is the chemotherapeutic agent that stops cancer multiplication and growth.
  • • Human Albumin is used to dissolve paclitaxel and facilitate its absorption into the cells.

Common side effects

  • • Loss of appetite
  • • Nausea, vomiting
  • • Irregular heartbeat
  • • Breathing issues
  • • Blood pressure fluctuations
  • • Mouth ulcers
  • • Skin rashes, itchiness
  • • Tiredness
  • • Hair loss
  • • Swelling of ankles

Serious Side Effects

  • • Bleeding in gastrointestinal tract
  • • Blood in urine and stool
  • • Severe fall in blood count
  • • Nerve Damage – loss of sensation
  • • Chest pain

Precaution

To be cautiously used in patient with –

  • • Irregular heartbeat
  • • Liver disease
  • • Low blood count
  • • Breathing disorder

Contraindications

Not to be used on people –

  • • Allergic to Paclitaxel
  • • Breastfeeding women
  • • Pregnant women

Warning

To be used under medical supervision, administered as a slow IV infusion over 30 minutes.

Important safety information

It should be regularly monitored for –

  • • Liver functions – elevated liver enzymes
  • • Blood count
  • • Renal functions
  • • Cardiac function monitoring

Storage:

Store the vial in its original carton at controlled room temperature between 20 °C and 25 °C.
Reconstituted suspension should be stored in the original carton at 2 °C to 8 °C.
Protect from bright light.
The reconstituted suspension should be used within 8 hours.
Discard any unused portion.

FAQ

Frequently Asked Questions

Which is the affordable paclitaxel –human albumin combination?

NAB-Paclikast
It is manufactured by Aprazer Healthcare.

Is there any premedication required with Nab-Paclikast (Paclitaxel) injection?

Steroids are not needed.
It does not contain allergic solvents.

It is advised to avoid driving for a few hours after Nab-Paclikast (Paclitaxel) injection. Why?

The formulation may contain alcohol.
It may lead to dizziness.

Can I replace Nab-Paclikast with traditional paclitaxel formulations?

It cannot be interchanged.
The absorption of both formulations varies from each other.

Are there specific instructions for hepatology patients?

It requires dose monitoring.

What functions are to be monitored with Nab-Paclikast (Paclitaxel) injection?
  • Blood count
  • Nerve functions
  • liver functions
  • Heart functions
  • Blood pressure
  • Kidney functions
Does Nab-Paclikast (Paclitaxel) injection affect your hair or skin?

It causes temporary effects on hair /skin.
The signs subside after treatment.

Which is the oncology injectable manufacturer?

Aprazer Healthcare is the oncology medicine manufacturer.