Piperaxis-4.5 gm

Piperaxis 4.5mg

Composition – Piperacillin 4 mg and Tazobactam- 0.5mg Injection

Classification – Antibiotic for ICU care

What is Piperaxis?

It is a combination of two types of antibiotics. Piperaxis injection is widely used in ICUs and for critically ill patients in hospitals to prevent the spread of life-threatening infections.

Uses of Piperaxis

• • Lower respiratory tract infections
• • Ventilator-associated pneumonia
• • Severe skin infection
• • Septic shock
• • Intra-abdominal infection
• • Urinary tract infections

How does Piperaxis work?

Piperacillin – It distorts the cell wall of bacterial cells, leading to cell death.
Tazobactam – It is used to prolong the effect of piperacillin and reduce resistance.

The common side effects of Piperaxis

• • Diarrhea
• • Bloating
• • Headache
• • Injury at the injection site

Severe side-effects

• • Allergic reaction
• • Severe skin rash
• • Seizure
• • Bloody diarrhea
• • Pain in the stomach
• • Cloudy urine
• • Lower back pain
• • Muscle weakness and cramps
• • Irregular heartbeat
• • Swelling in the body
• • Blurred vision
• • Chest pain
• • Confusion and dizziness

Why is Piperaxis widely used in the ICU?

• • It is effective against many types of bacteria
• • It lowers the risk of antibiotic resistance
• • It has increased efficacy

Precautions while using Piperaxis Injection

To be used carefully in patients with:

• • Renal dysfunction or renal injury
• • Bleeding disorders
• • Electrolyte imbalances
• • Neurological disorders
• • Cardiac issues
• • Hypertension
• • Bleeding disorders
• • Pregnancy and breastfeeding

Important Considerations for use in the ICU setting

Patients who are critically ill have altered excretion and metabolism.
The administered dose should be monitored to achieve the blood concentration.

Regularly Monitor –

• • Renal functions
• • Neurological functions
• • Blood functions
• • Gastrointestinal functions
• • Injection site

Drug Interactions

• • Vancomycin
• • Aminoglycosides
• • Anticoagulants
• • Vecuronium
• • Methotrexate

Administration Instructions

• • To be used as a slow IV infusion over 30 minutes.
• • It should not be mixed with Lactated Ringer’s solution.
• • Do not mix with blood or other drugs.

Contraindications

• • Do not use in case of severe allergy to the drug or its component.
• • In a severe medical condition.

Storage of Piperaxis Injection

• • Dry powder can be stored at room temperature.
• • The reconstituted solution can be stored at 2-8 degree Celsius for 48 hours.
• • Do not use diluted solutions stored at room temperature beyond 24 hours.

Warning

To be used under medical supervision only.

Aprazer Healthcare – Top Critical Care Medicine Manufacturer and Worldwide Availability

Aprazer Healthcare, manufacturing effective and safe injectables, is the leading pharmaceutical manufacturer for critical care generics.
We manufacture top-quality pharmaceuticals adhering to the WHO-GMP and EU-GMP standard practices.
Maintaining aseptic conditions and quality controls during manufacture and packaging, we manufacture sterile, precise-dose parenteral and critical care injections.