Description
TREXAZER 50MG
Composition: Methotrexate 50mg /2ml
Classification: Oncology Medicine
Trexazer: The Oncologist’s Preferred Choice for Cancer Care
Trexazer is widely prescribed by oncologists for its broad spectrum of action against multiple cancers.
Trusted and demanded its available worldwide in oncology care hospitals and clinics.
Aprazer Healthcare: Unbeatable Quality Anticancer Medicines
Aprazer Healthcare manufactures high-quality life-saving medicines and is the largest exporter worldwide.
- • WHO- GMP certified.
- • Available globally in 50+ countries.
- • Affordable Anticancer Medicines
What is Trexazer?
Trexazer is used as an anticancer medicine to effectively reduce cancer cell proliferation and growth.
Uses of Trexazer
- • Blood cancer
- • Breast cancer
- • Sarcomas
- • Solid tumors
- • Lymphomas
- • Arthritis
- • Psoriasis
How does Trexazer work?
It works by blocking folic acid synthesis in the cancer cells, which is used in cancer cell growth and division.
Common side effects
- • Nausea
- • Vomiting
- • Skin ulcers, rashes
- • Abdominal pain
- • Low blood count
- • Anemia
- • Risk of infections
- • Mouth ulcers
- • Alopecia
Serious side effects
- • Gastrointestinal bleeding
- • Lung inflammation
- • Jaundice, abdominal pain, dark urine color
- • Swelling, fluid retention
- • Serious allergic reaction – difficulty in breathing, skin rash
- • Intrathecal injection may cause seizure, headache, and confusion.
Precautions
To be used cautiously in
- • Renal impairments
- • Liver disorders
- • Bleeding disorders
- • Bone marrow suppression
- • Infections
- • Diabetics
- • GIT ulcers
Drug interactions
NSAIDS, probenicid, and penicillin increase methotrexate levels
Important Monitoring Considerations
- • Liver functions
- • Kidney functions
- • Blood count
- • Respiratory functions
- • Methotrexate serum levels as it’s highly toxic
- • Folic acid levels
Contraindications
- • Not to be used if any previous allergy or hypersensitivity to methotrexate or any excipients.
- • Breastfeeding mothers
- • Pregnant women
Important Handling Instructions
Due to its cytotoxic nature, Methotrexate should be handled while wearing gloves to minimize dermal absorption risk.
Needles or intravenous sets made of aluminum should not be used as they precipitate methotrexate and cause a loss of potency.
Storage
It should be stored at 2-8 degrees Celsius, protected from light.
Administration Instructions
- • To be administered Intravenously, IM, subcutaneously, or Intrathecal.
Warnings
To be used under the supervision of a medical practitioner or oncology specialist, having adequate diagnostic and monitoring facilities.
