Tudobest-LE
Tenofovir Disoproxil Fumurate, Efavirenz & Lamivudine Tablets IP 300mg/600mg/300mg
Tudobest LE
Composition:
Tenofovir – 300mg
Efavirenz – 600mg
Lamivudine – 300mg
Classification: HIV medicine
Tudobest LE: Globally Trusted for HIV Control
Tudobest is proven to suppress viral count and boost immunity. It is prescribed worldwide and stands out as an efficient, safe formulation.
Aprazer – Affordable HIV Solutions, Uncompromised Quality
- • Aprazer Healthcare leads the way in HIV drug development, manufactures a range of HIV medicines, including highly effective and widely prescribed, affordable treatments.
- • Manufactures a range of WHO-listed essential HIV medicines.
- • Our portfolio consists of all WHO-listed essential HIV drugs.
- • Cutting-edge manufacturing excellence
- • Continuous R&D – Aprazer continues to develop safe, effective HIV medicines.
- • Scientifically backed formulations
- • Regulatory compliant – WHO-GMP certified, meeting global safety and quality standards.
- • Worldwide reach – available in 50-plus countries
- • Affordable and accessible life-saving medicines.
What is Tudobest LE?
A potent drug combination used once a day for the treatment of HIV infection.
Uses of Tudobest LE
- • HIV infection
- • Prophylaxis of HIV
How does it work?
Inhibits viral DNA replication and multiplication, causing cell death.
Benefits
- • Potent viral suppression
- • Improves immunity
- • Well tolerated
- • Less frequent dosing
- • Lowers the chances of resistance
- • Prevents disease progression and transmission
Common side effects
- • Nausea
- • Vomiting
- • Diarrhea
- • Skin rashes and ulcers
- • Dizziness
Serious side effects
- • Lactic acidosis – buildup of lactic acid in the blood
- • Yellowish skin, urine, jaundice
- • Urine changes, fluid retention, swelling in the legs
- • Inflammation in the pancreas
- • Bone fractures, weakness, and pain in bones
- • Severe allergic reaction – breathing difficulty, rash, swelling
Precautions
To be used cautiously in:
- • Reduced renal functions – kidney disorders
- • Liver disorder
- • Osteoporosis
- • Elderly
- • Pregnant, lactating women
- • Co-infections (Hepatitis B)
- • Metabolic disorders – diabetes, obesity
Important Monitoring Instructions
- • Liver functions – HBV flare-ups
- • Kidney function – creatinine levels
- • Bone mineral density
- • Lactic acid levels in blood
- • Viral load and CD4 count
- • Lipid profile and glucose levels
Contraindications
- • Severe liver dysfunction
- • Hypersensitivity or allergic reaction to the drug or its excipients
Warnings
To be used under medical prescription.
Do not discontinue abruptly in Hepatitis B patients – may cause serious liver flare-ups.
Drug Interactions
- • Anticonvulsant drugs
- • Cardiovascular drugs
- • Antihypertensive
- • Anti-fungal
- • Anti-tubercular drugs
FAQ
Frequently Asked Questions
Which are globally prescribed tenofovir disoproxil fumarate/efavirenz /lamivudine tablets?
Tudobest tablets
It is manufactured by Aprazer Healthcare.
Can Tudobest LE cause long-term effects?
It can cause
- Bone loss
- Kidney dysfunction
- Weight loss
OTC pain relievers with Tudobest LE (tenofovir, efavirenz & lamivudine) are not safe. Why?
It may damage the kidneys.
Tenofovir / Efavirenz/ Lamivudine and alcohol use is not safe. Why?
It increases strain on the liver.
Do not leave Tudobest LE on your own. Why?
It can reactivate HBV.
Is it used in Hepatitis B HIV co-infections?
It can be used safely.
Tudobest LE is safe in liver cirrhosis. How?
It can be used in compensated liver cirrhosis.
Tudobest LE is used in people with kidney disorders. How?
It can be used with dose adjustment.
Name the reliable HIV medicine manufacturer?
Aprazer Healthcare is the Hepatology medicine manufacturer.
Reference Link
- https://pmc.ncbi.nlm.nih.gov/articles/PMC5111747/](https://pmc.ncbi.nlm.nih.gov/articles/PMC5111747/
- https://medlineplus.gov/druginfo/meds/a615044.html](https://medlineplus.gov/druginfo/meds/a615044.html
- https://medlineplus.gov/druginfo/meds/a614014.html](https://medlineplus.gov/druginfo/meds/a614014.html
