Virarazer

Tenofovir Disoproxil Fumurate, Emtricitabine & Efavirenz Tablets IP 300mg/200mg/600mg

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Description

Virarazer

Composition:
Tenofovir -300mg, Emtricitabine- 200mg, Efavirenz – 600mg

Classification: HIV Medicine

Virarazer: Powerful, Reliable HIV control

Virarazer is widely prescribed worldwide for powerful HIV suppression, leading to undetectable viral loads.

Aprazer Healthcare: Advancing Access to Lifesaving HIV Medicines

Aprazer Healthcare is a global pharmaceutical company and is the largest manufacturer and exporter of HIV medicines.

  • • Cutting-edge manufacturing excellence, ensuring safety, efficacy, and consistency
  • • Continuous R&D – Aprazer continues to develop safe, effective HIV medicines.
  • • Scientifically backed formulation, meeting global safety and quality standards.
  • • Regulatory compliant manufacturing facilities – WHO-GMP certified
  • • Worldwide reach – available in 50-plus countries
  • • Affordable and accessible life-saving medicines

What is Virarazer?

It is a fixed-dose combination used as a first-line treatment for HIV control.

Uses of Virarazer

  • • HIV-1 infections
  • • Post-exposure prophylaxis treatment

How does it work?

It mimics the DNA nucleotide bases, causes changes in the structure, and wrong cross-linking, causing viral cell death.

Common Side Effects

  • • Headache
  • • Dizziness
  • • Insomnia, nightmares
  • • GIT upset- diarrhea, nausea, vomiting
  • • Skin rashes
  • • Muscle pain

Serious Side Effects

  • • Neurological side effects (efavirenz) – depression, anxiety, seizures
  • • Liver dysfunctions- jaundice, hepatitis
  • • Kidney dysfunction – fluid retention, changes in urine
  • • Buildup of lactic acid in blood
  • • Bone loss – fractures, bone pain
  • • Hypersensitive reaction – fever, rash, swollen lymph nodes

Precautions

To be used cautiously in people with:

  • • Neuropsychiatric disorders
  • • Kidney diseases
  • • Liver diseases
  • • Pregnancy
  • • Breastfeeding
  • • Elderly patients
  • • Osteoporosis or people with a bone disorder
  • • Other drugs- risk of drug interactions

Contraindications

  • • Severe liver dysfunction.
  • • Severe kidney diseases
  • • Hypersensitivity or allergic reaction to the drug or its excipients.

Warnings

To be used under medical prescription.
Do not discontinue abruptly in Hepatitis B patients – may cause serious liver flare-ups.

Important Monitoring Considerations

Check for –

  • • Lactic acidosis
  • • Liver function – elevated liver enzymes
  • • Kidney functions
  • • Viral loads (HIV, HBV)
  • • Bone health
  • • Neurological condition
  • • Lipid profile and sugar levels

Drug Interactions

  • • Anticonvulsant
  • • Antifungals
  • • Cholesterol medicines- statins
  • • Anti-tubercular
  • • NSAIDs and other nephrology drugs
  • • Psychiatric medicines- sedatives, antidepressants

FAQ

Frequently Asked Questions

Take tenofovir disoproxil fumarate/emtricitabine /efavirenz tablets before meals. Why?

Take in the morning before food.
Food reduces absorption.

Take Virarazer tablets at bedtime. Why?

It causes dizziness.
It should be used at bedtime.

Can the Virarazer tablet cause CNS effects?

Efavirenz can cause
- Vivid dreams
- Abnormal thoughts
- Trouble concentrating

Is Virarazer given in pregnancy?

No, Efavirenz can harm the fetus.

It is harmful to breastfeed while on tenofovir disoproxil fumarate, emtricitabine /efavirenz therapy. Why?

It is usually not recommended.
It can pass into breast milk.

How long should I take the Virarazer tablets?

It is lifelong therapy.

Virarazer affects bone health. How?

Tenofovir disoproxil causes bone loss.