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Ulcerative Colitis and Its Treatment

It is an immune- mediated inflammatory disorder.

It damages the inner layer of the rectum or colon.

It causes inflammation and ulcers.

Early symptoms of ulcerative colitis-

Symptoms may come and go, followed by flare-ups.

  • Frequent watery stools
  • Blood in the stool
  • Mucus in the stool
  • Persistent abdominal pain and cramps
  • Strong sudden urge to defecate
  • Weakness or tiredness
  • Increased bowel frequency

Ulcerative colitis needs early management:

Symptoms for ulcerative colitis may be infrequent.

The inflammation continues to progress.

The risk of complications still exists.

Can ulcerative colitis be cured?

Ulcerative colitis does not have a specific medications.

The complications or symptoms can be managed.

Long-term management of ulcerative colitis-

The treatment approach aims to –

  • Reduce inflammation
  • Protect the gastrointestinal lining
  • Prevent flare-ups

Common medicines include:

5-aminosalicylic acid (5-ASA) medicines:

They include mesalamine, olsalazine, and sulfasalazine.

They reduce inflammation.

They may be used for a long duration.

They help manage mild to moderate condition.

Corticosteroids:

These are used to provide short-term relief.

They suppress the immune system.

They are used to manage acute flare-ups.

Immunomodulators:

  • Azathioprine
  • Mercaptopurine

These medicines may be used for long durations in selected people.

Biologics and small-molecule drugs:

These target specific pathways.

These are used in moderate to severe colitis.

They reduce the inflammatory and immune responses.

Commonly used medicine in ulcerative colitis:

Mesalamine is generally a well-tolerated 5-ASA derivative.

Mesalamine, available as Mesalzer, is manufactured by Aprazer Healthcare.

As a gastroenterology medicine manufacturer, we aim to manufacture affordable medicines without compromising quality.

We have a strong distribution network spanning Asian, African, and American countries.

Our portfolio comprises GIT-targeted drugs like:

  • Antibiotics for gastrointestinal infections
  • Ulcerative colitis medicines
  • Acid-relieving medicines

Why must I not stop medicines even if my symptoms subside?

Medicines must be stopped only after a doctor’s advice.

Symptoms may subside, but the condition may still prevail.

How does it cause blood in the stool?

The inflammation and open sores may induce bleeding.

Conclusion:

Ulcerative colitis requires long-term management.

The complications can be managed for long-term remission.