How Is Unsafe Sex Linked to Anal Cancer? And the Leading Risk Factor

It is the sexually transmitted infections that increase the risk of anal cancer.

The HPV infection forms a primary factor in the majority of cases.

HPV strains 16 and 18 directly cause changes in the anal cells.

It infects the inner lining of the anus.

It enters the body through sexual activity.

Genetic changes lead to rapid cell division.

What is Anal Cancer?

Anal cancer is formed in the anal canal. It is the last part of the digestive system.

It is a tube-like passage. It links the rectum to the anus.

What Are the Anal Cancer Types?

Squamous Cell Carcinoma – It is the cancer that occurs in the lining or the top skin layer covering the anus. It is usually caused by HPV or HIV infection. It is the common type of anal carcinoma.

Adenocarcinoma – It is a cancer that starts in the adrenal glands present in the organ. It is caused in the sweat glands, present in the skin around the anus, or the adrenal cells in the upper anal canal. It is a rare form of anal cancer.

What Are Anal Cancer Symptoms?

• • Bleeding through the anus
• • A lump or mass in the anus
• • Pain in the rectal area
• • Leaking of the stool
• • Changes in stool consistency and bowel movement
• • Abnormal rectal discharge
• • Discomfort in the rectum

Other Risk Factors for Anal Cancer

Having multiple sex partners – It increases the risk of infection.

The sexually transmitted viruses include –

• • HIV
• • HPV
• • Chlamydia

Anal sex- the infection enters through the anal route.

Smoking – use of tobacco or cigarettes, with years of use, increases the risk of developing cancer.

Age – The risk of anal cancer increases with age, above 50 -55.

Weak immune system – It increases the risk of HPV, HIV infections.

Previous cancer treatment – The radiation therapies used in ovarian or uterine cancer increase the risk.

Immunosuppressant – the weekend immunity increases the risk of cancer-causing infection.

The Anal Cancer Treatments

Surgery – It is the removal of the localized tumor. The tumor which has not involved the surrounding muscles and tissues.

Chemo-radiation forms an important part of treatment. It includes chemotherapy and radiation.

• • Radiation therapy – It is the use of high-intensity rays to kill cancer cells. It is focused on the tumor cells. It can be both internal and external.
• • Chemotherapy – The cytotoxic drugs kill the cancer cells. Given before surgery, it shrinks the tumor. It is given after surgery to eliminate leftover cancer cells. It is given in cycles with radiation therapy.

Chemotherapy Medicines Used in Anal Cancer

Two or more drugs are given in chemotherapy treatment at the same time to shrink the tumor/cancer.

The chemotherapy drugs are given in the form of cycles, including rest days.

The commonly used combinations involve –

• • 5-fluorouracil (5-FU) and Mitomycin.
• • 5-FU and Cisplatin(Cycokast)

For aggressive advanced stages of cancer, other drug combinations include-

• • Carboplatin(Carbokast) with paclitaxel (Paclikast)
• • 5-FU with cisplatin(Cycokast)
• • Oxaliplatin(Oxazer) , Leucovorin(Leucokast) and 5-FU
• • Docetaxel(Docekast) , Cisplatin(Cycokast), and 5-FU
• • Cisplatin(Cycokast) , Leucovorin(Leucokast) and 5-FU

The Trusted Anticancer Injections Manufacturer by Aprazer

With the evolving diagnostic landscape, we are focused on developing advanced anticancer medicines.

The innovative cancer treatments, including targeted anticancer medicines, chemotherapy medicines, increase the survival outcomes.

Aprazer is the leading oncology injectable manufacturer that develops advanced anticancer injections.

With a patient-centric approach and empathy, Aprazer develops a range of affordable generic anticancer medicines and anticancer injections.

• • WHO-GMP certified manufacturing capacities
• • Continuous Research and drug development
• • Leveraging cutting-edge technology

Aprazer’s products, owing to their high-quality standards and safety, are highly prescribed by leading oncologists in the world.

We are the bulk exporter of affordable anticancer injections to the leading hospitals, oncology care settings, and clinics.

Aprazer Healthcare, a long-standing leader in life-saving pharmaceuticals.