Abdominal Cramp Relief Medicines: Antispasmodic Combinations
Painkillers/muscle relaxant and anxiolytic agents
These are widely used to relax muscles in the gut.
These are significantly used to relieve muscle spasms caused in the GIT, bladder, or the gallbladder.
What are the commonly used Antispasmodic combinations?
- Antispasmodic + Analgesic medicine –
These relax the muscles and reduce spasm.
The painkiller reduces the pain.
It is widely used for abdominal spasm and pain.
Drotaverine + Paracetamol
Drotaverine + Mefenamic Acid
- Antispasmodic + Anxiolytic combination –
It is a combination of an anticholinergic with an anti-anxiety or tranquilizing agent.
It lowers the aggravated spasms caused by anxiety.
- Clidinium + Chlordiazepoxide
- Isopropamide + Trifluoperazine
What are the antispasmodic drug uses?
These are widely used to relieve muscle spasm and pain during –
- IBS
- Menstrual pain
- Abdominal colic
- Biliary and renal colic
Antispasmodic drug working –
The antispasmodic drugs work by inhibiting abnormal muscle contractions.
- Anti-muscarinic drugs – They block the cholinergic receptors.
This reduces the excessive muscular contraction.
- Dicyclomine
- Hyoscine butylbromide
- smooth muscle relaxants – These relax the smooth muscles in the gut and the bladder.
They relieve pain and muscle contractions.
- Drotaverin
- Mebeverine
- Calcium channel blockers – These inhibit the calcium channel, causing muscular contraction.
- Pinaverium bromide
- Otilonium bromide
What are the antispasmodic drug side effects?
The common side effects include-
- Dry mouth
- Constipation
- Dizziness
- Lightheadedness
- Drowsiness
- Weakness
- Blurred vision
- Decreased sweating
How do antispasmodic drugs differ from antispastic drugs?
Antispasmodic drugs relax smooth muscles.
It helps relieve smooth muscle contractions.
These are mainly used to control involuntary muscle spasm.
Antispastic drugs are used to relax skeletal muscles.
They are used to relieve back pain.
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