Mycophenolate Mofetil (Myfocept 500) – The Foundation of Transplant Success
Mycophenolate Mofetil is the core therapy drug to prevent acute organ rejection.
Mycophenolate Mofetil is available globally as Myfocept 500 and Myfocept 250.
It is a first-line drug in anti-rejection therapy.
What is Mycophenolate Mofetil (Myfocept 500)?
Mycophenolate Mofetil is an immunosuppressant drug.
It is widely used in organ transplant drug regimens.
It lowers immune activity and prevents the body’s rejection of the foreign organ.
Used in solid organ transplants –
- Liver transplant
- Kidney transplant
- Heart transplant
Aprazer Healthcare (pharmaceutical manufacturer) specializes in manufacturing specialty medicines.
We manufacture a global range of immunosuppressive agents and chronic disease medicines.
We are the leading specialty medicine exporter from India.
Manufacturing global standard drugs, Aprazer Healthcare’s products are accepted worldwide.
We supply immunosuppressive drugs to the leading hospitals and clinics.
How is Mycophenolate Mofetil (Myfocept 500) used in organ transplant therapy?
It forms an important part of the organ rejection drug regimen.
It is combined with other drugs, forming a triple–drug regimen.
- Mycophenolate Mofetil – It inhibits the formation of white blood cells.
These cells actively attack the new organ, causing immune rejection.
- Calcineurin inhibitor– It halts the activation of the T cells (white blood cell type).
It down regulates the immune action of the T-cells.
- Corticosteroid– It reduces the inflammation caused by transplant and suppresses immune flare.
Why is Mycophenolate Mofetil (Myfocept 500) combined with other drugs?
When combined with other drugs
- It offers better immune suppression
- It can be used in smaller doses
- It prevents acute rejections
- It offers lower side effects
- It offers longer graft and patient survival
The standard adult dose of Mycophenolate Mofetil (Myfocept 500)
Kidney transplant – For kidney transplant, the standard daily dose is 2g.
Liver /Heart transplant- For liver and heart transplant, the standard daily dose is 3g
Elderly patients – For elderly patients, the initial drug dose is low (500 mg).
Why is Mycophenolate Mofetil (Myfocept 500), the foundation for the anti-rejection regimen?
Targeted action – It specifically targets T and B lymphocytes.
It lowers harmful effects on other blood cells.
Lower steroid doses required- It is highly effective and requires low doses of corticosteroid, preventing steroid side effects.
Non-nephrotoxic – It does not harm the kidneys compared to other drugs.
It can be used long-term for organ preservation.
