Abiraterone Acetate Tablets

Abiraterone Acetate

Classification: Anticancer Medicine

What is Abiraterone Acetate?

Abiraterone is a hormone therapy drug. It is used for resistant prostate cancers. It is given with prednisolone to prevent hormonal fluctuations. It is often combined with other drug therapies.

Uses of Abiraterone Acetate

It is widely used to inhibit the spread and growth of prostate cancer to other organs. It is used in advanced cancer or those not responding to androgen deprivation therapies.

• • Advanced Hormone-sensitive prostate cancer
• • Castration-resistant prostate cancer (CRPC)

Abirakast (Abiraterone Acetate) – Affordable Prostate Cancer Medicine

Abirakast is abiraterone acetate produced by Aprazer Healthcare. Abirakast is widely available worldwide and is the leading pharmaceutical brand offering high-quality abiraterone acetate for effective cancer treatment.

Affordable and accessible, Abirakast 500mg & Abirakast 250mg is an oncologist’s preferred choice.

Aprazer Healthcare – Leading Oncology Products

Aparzer Healthcare, manufacturing global standard anticancer drugs, is the leading oncology drug manufacturer.

Maintaining the highest quality standards, WHO-GMP qualified manufacturing, stringent quality controls, accompanied by research-driven innovation, we are top oncology drug manufacturers and exporters delivering affordable, high-quality cancer drugs worldwide.

Our extensive portfolio includes a range of hormonal therapy drugs, targeted therapy drugs, and a complete range of chemotherapy drugs.

We are the leading anticancer drug exporter to countries in Southeast Asia, South Africa, and South America.

Mechanism of Working for Abiraterone Acetate

It inhibits the testosterone-producing enzyme. Testosterone is an endocrine hormone used by prostate cells for growth and proliferation. Inhibiting testosterone causes the shrinking of the tumor and inhibits further growth and proliferation.

Benefits of Abiraterone Acetate

It is used to prolong survival and is widely used to relieve cancer complications like pain or decline in skeletal functions.

• • Delays disease progression
• • Improves survival and quality of life
• • Reduces cancer complications

Common Side Effects

Abiraterone acetate is well tolerated, and the common side effects are manageable and treated by cancer supportive care.

• • Tiredness
• • Joint pain
• • Hot flashes
• • High blood pressure
• • Urinary tract infection
• • Low potassium levels that cause muscle twitching
• • Respiratory infection
• • Diarrhea
• • Fluid retention
• • High cholesterol levels
• • Skin rashes

Serious Side Effects

The serious side effects include adrenal hormone fluctuations, as it increases cortisol levels and causes an imbalance in other mineralocorticoid secretion. It is usually caused by not taking prednisolone during the therapy. The symptoms include dizziness, unusual tiredness.

It may cause severe cardiovascular side effects in people with heart disorders and can lower blood sugar in diabetics. The symptoms consist of a fast heartbeat, sweating, and weakness, etc.

Allergy or Hypersensitivity: Immediate reaction to the drug component, causing skin rash, shortness of breath, and swelling in the face, tongue, etc.

Contraindications

• • It should not be used by people who have any allergy to drug components.
• • Abiraterone is not recommended for use in women and children.
• • It should not be used by breastfeeding mothers and pregnant women, as it may cause harm to the fetus.

Precautions while using Abiraterone Acetate

To be used cautiously in patients with –

• • Cardiac abnormalities
• • Hepatic impaired functions
• • Renal impaired functions

Warnings

It is a prescription drug. It should not be used without a doctor’s advice.

Drug Interactions

Abiraterone may show serious drug interactions with ongoing treatment, illness, or medications, anticonvulsant, diabetic, or cardiovascular drugs.

Important Safety and Monitoring Information

Abiraterone use for long-term hormonal therapy can cause hormonal or blood changes. Routine checkup of blood count, liver functions, electrolyte status, and cardiac functions.