Pain-relieving medicine

Aceclofenac, Paracetamol & Serratiopeptidase Tablets

Aprazer Healthcare – Leading WHO-GMP certified manufacturer and global exporter of Aceclofenac, Paracetamol & Serratiopeptidase Tablets (Apraflex SP). High-quality, reliable, affordable medicine.

Formulation Tablets
Standard WHO-GMP Certified Quality
Supply Type Global Export & Institutional Supply
Finished Commercial Brand

Available finished formulation under our brand name APRAFLEX SP.

View Commercial Product Details
WHO-GMP Certified
Global Export Ready
Quality Assured

Formulation Insights

Comprehensive Medical Overview

Aceclofenac, Paracetamol & Serratiopeptidase

Classification: Pain-relieving medicine

What is the Aceclofenac, Paracetamol & Serratiopeptidase combination?

It is a combination of an NSAID, paracetamol, and a proteolytic enzyme.

It is used to treat conditions with pain /swelling.

Apraflex SP is a painkiller manufactured at Aprazer Healthcare (WHO-GMP compliant facility).

With a global distribution network, we supply drugs to Asia, Africa, and America.’

We are a recognized and accepted brand in the international markets.

Our generic product portfolio comprises a global range of NSAID combinations.

Aceclofenac, Paracetamol & Serratiopeptidase combination is used for -

Effectively reducing pain and swelling, it brings symptomatic relief in –

• Arthritis
• Musculoskeletal pain
• Low back pain
• Dental pain
• Post-operative inflammation

Aceclofenac, Paracetamol & Serratiopeptidase combination working -

Aceclofenac – It inhibits the enzyme that induces prostaglandin secretion.

Inhibiting prostaglandins helps relieve pain and inflammation.

Paracetamol – It works on the CNS, reducing the threshold for pain.

Serratiopeptidase – It is a proteolytic enzyme.

It helps manage inflammation.

Aceclofenac, Paracetamol & Serratiopeptidase side effects -

The common side effects include –

• Digestive issues
• Mild skin rashes
• Dizziness

The side effects that require consulting a doctor –

• Black, tarry stool
• Severe allergy
• Dark urine
• Yellowish skin
• Decrease in urination
• Swelling in legs /ankles
• Shortness of breath

Aceclofenac, paracetamol & serratiopeptidase combination warnings -

It is contraindicated in –

• Active stomach ulcers
• Severe organ failure
• Previous history of allergies to NSAIDs or aspirin
• Third trimester of pregnancy

Be careful with other paracetamol-containing preparations to avoid paracetamol overdose.

People using blood thinners must not combine it with NSAIDs as it may increase the risk of bleeding.

NSAIDs may be risky in people with heart disorders. It may increase the risk of cardiac events.

The use of the medicine must be reported to the doctor before surgery as it may affect blood clotting.

Alcohol may adversely affect the liver/stomach.

Aceclofenac, paracetamol & serratiopeptidase combination’s interactions with other drugs -

Drugs that must be used with extreme caution-

• Anticoagulants /antiplatelets - These may increase the risk of severe bleeding.
• Other NSAIDs – These cause stomach irritation and kidney injury.
• Diabetic drugs – A regular high dose of NSAIDs may interact with diabetes management.
• Blood pressure medicines – Aceclofenac reduces the efficacy of certain BP drugs.

NSAIDs reduce the renal clearance of certain drugs, increasing toxicity.

• Methotrexate
• Lithium drugs

Corticosteroids, when used with aceclofenac, may lead to severe digestive tract bleeding.

FAQ

Frequently Asked Questions

Why must an NSAID combination be avoided on an empty stomach?

Taking it on an empty stomach increases gastric irritation.

Is this combination used for a simple cold or fever?

It must not be taken for a mild cold.
It is taken for appropriate pain and inflammation.

Do NSAIDs interact with blood pressure medicines?

Aceclofenac reduces the effectiveness of certain blood pressure–lowering drugs.

Why is an antacid given with the aceclofenac, paracetamol & serratiopeptidase combination?

Yes, it reduces stomach upset.
It does not prevent all GIT injuries caused by the NSAIDs.

Can it be used in asthma patients?

It must not be used in asthma unless recommended.
It can trigger an asthma flare.

Which is the pharmaceutical drug manufacturer for NSAID combinations?

Aprazer Healthcare is a global generic drug manufacturer.