Anastrozole Tablets

Anastrozole

Classification: Anticancer Medicine

What is Anastrozole?

It is widely used to treat breast cancer that may be hormone-dependent or not dependent on hormones. It is widely used in elderly women after the cessation of the menstrual cycle.

Uses of Anastrozole

• • It is used after surgery to prevent cancer recurrence.
• • In advanced breast cancer that has spread to different body parts.
• • In males, for cancer in the breast.
• • In cancers that do not respond or develop resistance to tamoxifen.

Anzakast (Anastrozole) – Used for Tamoxifen-Resistant Breast Cancers

Anzakast is anastrozole and is widely prescribed for breast cancer in both males and females. It is used along with radiation therapy or surgery to shrink tumors and treat initial and resistant cancers.

Anzakast, available worldwide, is highly affordable, offering a reliable, cost-effective anticancer treatment option.

Aprazer Healthcare – Affordable Generic Anticancer Drugs

Aprazer Healthcare is the leading pharmaceutical company, pioneering advanced anticancer medicines and therapies. We are the leading anticancer medicine manufacturer, strongly compliant with the highest global standards (WHO-GMP, EU-GMP).

With Global distribution and a robust supply chain, we are the leading anticancer medicine exporter, committed to making anticancer treatment and medicines accessible to the last mile.

Working of Anastrozole

It inhibits the formation of estrogen. It deregulates the enzyme that converts androgens to estrogen. It reduces the level of estrogen and inhibits tumor growth caused by estrogen.

Anastrozole side effects

The side effects caused by anastrozole are mainly due to the reduced estrogen levels.

• • Hot flushes and sweating- Reduced estrogen levels affect the body’s temperature regulation.
• • Pain in joints – it decreases lubrication in the joints.
• • Nausea, Diarrhea
• • Mood swing and depression
• • Headache
• • Reduces lubrication in the vagina
• • Fluid retention and swelling in joints and ankles
• • Hair thinning due to hormonal changes
• • Numbness or pain in the fingers and toes

Serious side effects

• • Bone weakening – it increases the risk of bone fractures and causes mineral loss.
• • Heart complications – Anastrozole increases cholesterol levels and increases the risk in people with cardiac issues.
• • Allergic reaction – it may not be suitable for certain people and may cause an anaphylactic shock or immediate reaction.
• • Liver dysfunction – Anastrozole increases levels of liver enzymes.

Warnings to be followed when using Anastrozole

• • It should be used when prescribed by a doctor.
• • Should not be used in allergy or hypersensitivity to drug components.
• • It should not be used in young women and children.
• • To be used in elderly women.
• • Avoid pregnancy or breastfeeding, as it causes harmful effects to the fetus.

Precautions Using Anastrozole

Anastrozole should be used cautiously in people with –

• • Heart disorders- It may increase the risk of angina or a heart attack.
• • High cholesterol – an increase in cholesterol may increase the risk of stroke.
• • Liver disorders – It can cause hepatotoxicity, severely affecting liver functions.
• • Osteoporosis –It loses the bone mineral density and an increased rate of fracture.

Important Monitoring Considerations

The long-term use of Anastrozole therapy, lowering estrogen levels, should be monitored for –

• • Heart functions
• • Cholesterol levels
• • Bone mineral density
• • Liver functions

Storage of Anastrozole tablets

Anastrozole tablets should be stored in an air-tight container, away from light, heat and extreme temperatures.

Drug Interactions

• • Do not combine Anastrozole with other estrogen-lowering drugs.
• • Tamoxifen – It reduces the effectiveness of anastrozole.
• • Anticoagulants may increase the risk of bleeding.
• • It should be used cautiously when taking painkillers or psychotic drugs.
• • Health supplements like whey protein reduce their effectiveness
• • Avoid grape-fruits.