Bosentan Tablets

Bosentan Tablets

Classification: Pulmonary Hypertension Medicine

What is Bosentan?

Bosentan is used to treat hypertension in the blood capillaries of the lungs.

Uses of Bosentan?

• • Pulmonary Arterial Hypertension
• • Idiosyncratic Pulmonary Arterial Hypertension
• • Prevent ulcers on the digits- fingers and toes.

Bosenzer – Recognized Treatment for Pulmonary Hypertension

Bosenzer, developed by Aprazer Healthcare, is the top-prescribed bosentan therapy worldwide. Bosenzer, trusted by leading cardiologists and medical practitioners, leads in quality and efficacy parameters.

Bosenzer is widely used to improve exercise capacity and delay disease progression.

Aprazer Healthcare – Top Indian Anti-hypertensive Medicine Manufacturer and Exporter

Aprazer Healthcare specializes in specialty care, manufacturing a wide range of life–saving medicines and rare disease medicines to meet the unmet needs.

Aprazer Healthcare is the leading Hypertensive medicine manufacturer, blending science and cutting-edge technology, bringing the latest advanced treatments available worldwide.

Working of Bosentan

Bosentan works by reducing constriction in small blood vessels in the lungs. It improves the flow of blood to the lungs.

Common Side Effects of Bosentan

Bosentan causes dilatation and relaxation of blood vessels. It affects vascular tone throughout the body and causes –

• • Headache
• • Flushing
• • Fluid Retention
• • Respiratory tract infections
• • Low blood-pressure
• • Diarrhea
• • Fatigue
• • Joint pain
• • Chest pain
• • Heart palpitation

Serious Side Effects of Bosentan

The rare and serious side effects caused by Bosentan include a lowering of the blood count and liver disorders. It is highly dependent on dose.

• • Allergic reaction – It consists of a severe allergy or reaction to drug components.
• • Hepatotoxicity – It can cause liver injury and increase liver enzymes.
• • Anemia – It reduces the blood count, RBCs, and WBCs.
• • Fluid Retention – It causes swelling and edema in the ankles and joints.
• • Infertility in males – It decreases sperm count and raises the risk of infertility.

Precautions While Using Bosentan

Various precautions are necessary to be maintained during treatment due to its severe toxicity and side effects. Regular monitoring of vital functions is required –

• • Liver functions
• • Heart functions
• • Kidney functions

Effective contraception should be maintained as it can cause fatal harm or damage.

Warning Using Bosentan

• • It should be prescribed by the doctor.
• • It should not be used in breastfeeding and lactating mothers.
• • It should not be used in allergy or hypersensitivity to the drug.
• • It should not be taken with alcohol.

Important Monitoring Considerations

Bosentan should be used carefully in pre-existing medical conditions and should be monitored for –

• • Elevated liver enzymes
• • For signs of infection
• • Blood count

Drug Interaction With Bosentan

Due to the risk of side effects, it should not be combined with –

• • Antifungals
• • Hypertension medicines
• • Antibiotics
• • Anticoagulants
• • Immune suppressants
• • ED medicines
• • Anti-diabetics

Storage

Bosentan tablets should be stored in the original box, away from light and moisture. It should not be stored above room temperature.

Conclusion

Long–term use of Bosentan therapy should be carefully assessed for any medical conditions and regularly monitored for severe side effects.