SULBAXIS
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Cefoperazone & Sulbactam

Composition: Cefoperazone – 1000mg & Sulbactam – 500mg

Classification: Antibiotic Injection

What is Cefoperazone and Sulbactam Injection?

It is composed of two antibiotics, which provide a prolonged antibiotic effect against many bacterial strains.

Uses of Cefoperazone and Sulbactam Injection

  • • Upper respiratory tract infections
  • • Urinary Infections
  • • Gastrointestinal infections
  • • Blood infections
  • • Meningitis
  • • Skin infections
  • • Genital infections
  • • Bone infections

Sulbaxis – Trusted Antibacterial Combination

Sulbaxis is used in ICU centers and hospitals to prevent several types of infections in critically ill patients. Trusted worldwide, Sulbaxis is used to prevent the spread of bacterial infection in hospitals and critical care departments. It is used to treat infections that are not cured by cefoperazone.

Aprazer Healthcare – Highest Manufacturing Standards

Adhering to the global manufacturing standards, Aprazer Healthcare is the leading pharmaceutical company focused on manufacturing top-quality anti-infective and antibiotic preparations.

We continue to invest in new therapies and advanced antibiotic treatments, combating antimicrobial resistance.

As a leading antibiotic injection manufacturer and exporter, Aprazer Healthcare stands as a major player in global pharmaceutical markets and Indian pharma exports.

Mode of Action of Cefoperazone and Sulbactam Injection

Cefoperazone, when combined with sulbactam, prolongs its effects.

Cefoperazone – It destroys the bacterial cell membrane.

Sulbactam – It increases the effect of cefoperazone.

Common Side Effects

Cefoperazone and Sulbactam Injection causes gastrointestinal and bleeding side effects.

  • • Pain, swelling at the site of injection
  • • Nausea
  • • Diarrhea
  • • Decreased blood count
  • • Headache
  • • Dizziness
  • • Skin rashes

Severe Side Effects

  • • Severe Allergic Reaction – An allergic reaction can be fatal, and it develops soon after the administration of the injection.
  • • Reduces Clotting Time – It affects people with bleeding disorders and causes bruising.
  • • Hepatic and Renal Dysfunctions – It can cause severe acute hepatic and renal toxicity at high doses.
  • • Diarrhea – It can disrupt gastrointestinal functions, causing bloody diarrhea or watery stools.
  • • Seizures – Overdoses in kidney dysfunctions can cause seizures.

Precautions for the use of Cefoperazone and Sulbactam injection

It should not be used in people with an allergy to drug components.
It should be used with a doctor’s advice.
Do not use alcohol during the treatment.

The dose should be adjusted and monitored in –

  • • Kidney patients
  • • Bleeding disorders
  • • Gastrointestinal issues
  • • Pregnant and breastfeeding women

Important Monitoring Instructions

To avoid severe complications, regular monitoring for unusual bleeding, bruising, blood in stool and organ functions like liver and renal functions is required.

Administration Instruction

It should be given as a slow IV infusion or as direct IV or Intramuscular injection.

Drug interactions

Cefoperazone and sulbactam may interact with other drugs and cause serious complications.
Prevent mixing with –

  • • Anticoagulants
  • • Aminoglycosides
  • • Diuretics

Storage

An unconstituted solution can be stored at room temperature.
Constituted should be stored at refrigerator temperatures (2-8 °C) degree Celsius.
Prevent from Heat and light.