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Ceftriaxone Injection
Classification: Antibiotic Injection
What is Ceftriaxone Injection?
Ceftriaxone is a strong antibiotic effective against numerous bacterial strains. It prevents several infections before and after the surgery.
Uses of Ceftriaxone Injection
It is widely used against several bacterial infections –
- • Respiratory tract infections
- • Skin infections
- • UTI
- • Gonorrhea
- • Meningitis
- • Blood infections
- • Bone and joint infections
The Best Ceftriaxone Injection – Aptriax
Aptriax is used in the ICU care setting and hospitals to prevent the spread of bacterial infections in critically ill patients. Aptriax is trusted worldwide and used for ear, lung, and brain infections. It prevents the spread of infections in ICUs.
Aprazer Healthcare – Unparalleled Antibiotic Range
Aprazer Healthcare is the leading company manufacturing top–quality antibiotics at par with international standards and meets global demands. Aprazer Healthcare offers an extensive portfolio that comprises generic antibiotics and branded antibiotics.
Aprazer Healthcare is the leading pharmaceutical exporter of antibiotic drugs, expanding its reach to the global corner and underserved communities.
Mode of Working of Ceftriaxone Injection
Ceftriaxone injection has a potent antibacterial effect. It damages the outer cell wall and causes bacterial cell death.
The Common Side Effects of Ceftriaxone Injection
Ceftriaxone causes mild side effects due to its effect on the gut.
- • Nausea
- • Vomiting
- • Diarrhea
- • Abdominal Pain and Cramps
- • It can cause pain and swelling at the injection site.
Serious Side Effects
Allergic Reaction – Any allergy or hypersentivity can cause a severe allergic or anaphylactic reaction. It can cause a painful skin rash, shortness of breath.
Severe GIT Side-effects – It disturbs the gut flora and causes the risk of opportunistic bacteria.
Lowers The Blood Count – Ceftriaxone causes depletion of red blood cells and platelets.
Seizures – It can cause mental changes in people with kidney dysfunction.
Important Precautions and Warning Instructions
- • It should be used in hospital care settings under supervision.
- • It should not be used in people with kidney dysfunction and liver diseases.
- • It should be avoided in mothers who are lactating.
- • It should not be used in pregnancy.
- • It can cause neurological side effects; driving must be avoided.
- • It should not be used in an allergy to the drug.
- • The course of the antibiotic should be completed.
Important Administration Instructions
Ceftriaxone injection should be administered as a slow IV infusion or intramuscular.
Storage of Ceftriaxone Injection
Ceftriaxone powders should be stored at 15-30 degrees Celsius. Reconstituted solution should be stored at 2-8 degrees and used within 24 hours.
Drug Interactions
It should not be mixed with Ringer’s solution or other calcium elements.
- • Oral Calcium supplements
- • Calcium injections
- • Warfarin
- • Live cholera vaccine
- • Polysaccharide typhoid vaccine
Important Monitoring Considerations
Regularly monitor the infection symptoms and neurologic functions.
- • Blood count
- • Skin reactions
- • Cardiac functions
- • Kidney functions
- • Liver functions
- • Bloody diarrhea
- • Injection site irritation or pain
- • Superinfections
Key Takeaways
Ceftriaxone injection is a third-generation cephalosporin, widely used for its antibiotic effect against complicated bacterial infections. Ceftriaxone injection should be carefully used and monitored for its adverse effects.
