Ceftriaxone & Sulbactum Injection

Ceftriaxone and Sulbactum Injection

Classification – Antibiotic Injection

What is Ceftriaxone and Sulbactam Injection?

It is a broad–spectrum antibiotic. It is widely used in ICU care settings.
It is used to treat infections in hospitals. It is widely used in critically ill patients.

What is Ceftriaxone and Sulbactam Injection Used for?

It is used for severe infections.

• • Respiratory tract infections
• • Skin infections
• • UTI
• • Gonorrhea
• • Meningitis
• • Blood infections
• • Bone and joint infections

What is Aptriax-S Injection?

Aptriax- S injection manufactured by Aprazer Healthcare.
It is a strong antibiotic.
Aptriax –S injection is used in ICU settings to control hospital-acquired infections.
It is used to treat bacteria that are resistant to other antibiotics.

Aprazer Healthcare – The Leading Company Manufacturing Antibiotic Injections

Equipped with the latest technology, we manufacture advanced antibiotic injections.

• • Ready to use technology injections.
• • Prefilled syringes.

Aprazer is the top Indian ICU injection manufacturing company.
We specialize in manufacturing global standard medicines.
Our products are quality-efficient and globally accepted.
We are the leading ICU injection medicine exporters to countries worldwide.

Our product catalogue consists of a range of antibiotics.

• • Piperacillin and Tazobactam Injection 4.5mg – Piperaxis-4.5 gm
• • Cefoperazone & Sulbactam injection 1.5mg – Sulbaxis

Working of Ceftriaxone and Sulbactam

It is a combination of two drugs.
Ceftriaxone is the primary agent. It disintegrates the cell membrane.
Sulbactam prolongs effects. It increases antibiotic efficacy.
It inhibits the lactamase enzyme.

What Are the Ceftriaxone and Sulbactam Side Effects?

It is mild and tolerated.
It interrupts the gut biome. It kills the normal bacteria.
It leads to toxin production.

• • Dark stool
• • Chest pain
• • Chills and fever
• • Painful urination
• • Sore throat
• • Ulcers
• • Swollen glands and lymph nodes
• • Bleeding
• • Weakness
• • Diarrhea
• • Skin rashes

What Can Be Ceftriaxone and Sulbactam Serious Side Effects?

It affects the liver and kidney functions.
It leads to an immune response.

• • Anaphylactic reaction

Gastrointestinal Issues –
It can cause –

• • Inflammation in the pancreas.
• • Severe stomach cramps
• • Watery diarrhea.
• • Calcium stones in the gall bladder.

Bleeding Issues –

• • Blood in stool
• • Severe anemia

Superinfections – It reduces healthy bacteria.

Neurological side-effects –
It leads to convulsions, confusion.
It can cause tremors.

Why Use Ceftriaxone and Sulbactam Injection Cautiously?

Use carefully in people with –

• • Liver disorders
• • Kidney disorders
• • Diabetes
• • Gastrointestinal disorders
• • Pregnant women
• • Breastfeeding women

How to Inject Ceftriaxone and Sulbactam Injection?

It should be administered as IV/IM

• • Slow IV infusion (30-60 minutes).
• • It is mixed with lidocaine.
• • Avoid mixing with Ringer’s solution or calcium-containing ingredients.

Why Monitor Blood Functions in Ceftriaxone and Sulbactam Therapy?

It can alter the clotting time.
It reduces blood count.
It requires monitoring of –

• • Blood count
• • Bleeding time
• • Kidney functions
• • Liver functions

It reduces the effective bacteria in the gut.
It should be regularly monitored for superinfections.

How to Store Ceftriaxone and Sulbactam Injection?

The unopened vial should be stored at 20 -30 degrees.
The reconstituted solution is to be stored at 2-8 degrees Celsius.
The solution can be stored for 24 to 48 hours.
The solution is stored at room temperature to be used for 6-24 hours.

One Should Not Use Ceftriaxone and Sulbactam Injection in –

Avoid its use in –

• • Allergy to the drug component.
• • In severe liver or kidney disorders.
• • In bleeding disorders.

What to Avoid With Ceftriaxone and Sulbactam Injection?

• • Calcium medicines – They can form precipitates.
• • Anticoagulants – They increase bleeding risk.
• • Live vaccines – They affect bacteria in the vaccines.
• • Aminoglycoside antibiotics – They cause ear and kidney toxicity.
• • Oral contraceptives – The injection reduces their efficacy.
• • Immune modulating drugs – They interfere with their activity.

Conclusion

Ceftriaxone and Sulbactam injection are widely used in infections.
It cannot be administered by oneself.
To be administered by a doctor only.
It should be carefully monitored for superinfections and bleeding issues.
Take with food and drink enough water. It reduces stomach upset.