Daclatasvir and Sofosbuvir Tablet

Daclatasvir and Sofosbuvir Tablet

Classification: Hepatitis C medicine

What are the Daclatasvir and Sofosbuvir Tablets?

It is a combination of two antiviral medicines, used for effective Hepatitis C treatment. It is used as a single-pill regimen for effective Hepatitis C control.

Uses of Daclatasvir and Sofosbuvir Tablets

• • It is widely used to treat Chronic Hepatitis C.
• • It is effective against multiple Hepatitis C strains.
• • It can be used in adults and children below 14 years of age.
• • It can be used in severe liver or kidney disorders, and can be used in HIV co-infections.

Sofokast Plus (Daclatasvir and Sofosbuvir) – Pan-genotypic Hepatitis C Medicine

Sofokast Plus is an affordable Hepatitis C medicine and offers a trusted single-pill regimen treatment for multiple hepatitis c strains. Sofokast Plus is approved and WHO-GMP certified treatment for Hepatitis C.

It is used worldwide by the top leading hospitals and hepatologists to effectively suppress viral count.

Aprazer Healthcare – Leadership in Hepatitis C Care

Aprazer Healthcare is one of the major generic medicine manufacturers. We specialize in manufacturing both generic and specialty products.

Recognized worldwide due to its global reach and large-scale production, Aprazer Healthcare marks a benchmark in the production of top–quality hepatitis C medicines. We are the leading hepatitis C medicine exporter across 50 + countries, delivering premium quality world-standard Hepatitis C medicines.

Working of Daclatasvir and Sofosbuvir Tablets

It consists of two drugs that offer additive viral suppression.

Daclatasvir – It binds to the viral proteins and interrupts viral assembly.

Sofosbuvir – It disrupts DNA replication and multiplication.

Sofosbuvir stops viral multiplication, and daclatasvir stops the viral linking process. Together, they form a strong combination, working in synergy.

Common Side Effects of Daclatasvir and Sofosbuvir Combination

The side effects caused by the Daclatasvir and Sofosbuvir combination are generally well-tolerated and settle on their own.

The side effects are caused due to their potent antiviral activity and increased workload on the immune system.

• • Headache
• • Nausea
• • Weakness
• • Insomnia
• • Skin rash
• • Opportunistic infections

Severe Side Effects of Daclatasvir and Sofosbuvir

The two antiviral drugs are generally well tolerated; the severe side effects are caused by some drug interaction or other existing health condition.

• • Bradycardia – it is caused when given with amiodarone.
• • Liver Toxicity – it is caused in patients with cirrhosis, liver failure, and Hepatitis B patients.
• • Anemia – it causes anemia when combined with ribavirin.
• • Neurological Effects – it is caused in people with bleeding disorders, causing confusion, headache, and dizziness.

Precautions While Using Daclatasvir and Sofosbuvir Tablets

Daclatasvir and sofosbuvir tablets should be used cautiously in people taking other medicines and those having other diseases.

Careful dose monitoring is required for people with –

• • Heart diseases
• • Severe liver and kidney disorders
• • Bleeding disorder
• • Drug interactions
• • Hepatitis B co-infections

Warnings Using Daclatasvir and Sofosbuvir Tablets

• • It should be used only after a doctor’s advice.
• • It should not be used in pregnant or breastfeeding mothers.
• • Women should maintain effective contraception during the treatment.

Important Safety and Monitoring Information

Using long-term Daclatasvir and sofosbuvir treatment should be carefully monitored for drug interactions and other illnesses.

The patient must be monitored for a –

• • Slow heartbeat.
• • Hepatitis B reactivation
• • Liver and kidney functions

Storage

The Daclatasvir and sofosbuvir tablets should be stored at normal temperature.

It should be protected from heat, light, and moisture.

Drug Interactions

It interacts with several drugs to cause adverse effects-

• • Antifungal medicines
• • Antiepileptic medicines
• • Antiviral medicines
• • Antibiotics
• • Anticonvulsants
• • Corticosteroids