Hydrocortisone Sodium Succinate Injection
Hydrocortisone Sodium Succinate Injection
Classification: Steroid
What is Hydrocortisone Injection For?
It is a corticosteroid. It is used to treat emergency conditions for a fast-acting response.
It is used to rapidly control allergies or inflammatory responses.
Where is Hydrocortisone Injection Used?
It treats conditions when the body shows immune overactivity.
- • Severe allergies
- • Adrenal crisis
- • Acute episode of rheumatoid arthritis
- • Asthma attacks
- • Ulcerative colitis flare-ups
- • Severe skin rashes
- • Eye inflammation
- • Blood disorders
- • Certain cancers
What is Hyaxis?
It is Hydrocortisone Injection manufactured by Aprazer Healthcare.
Hyaxis is used in the leading hospitals and in emergency wards. Hyaxis is used to treat immediate medical conditions.
It is widely used in trauma care centers to tackle acute asthma attacks or conditions of shock.
Aprazer Healthcare – The Leading Emergency Care Injection Manufacturer
Aprazer Healthcare is a globally recognized Indian pharmaceutical company manufacturing top-quality medicines and injections.
We are the top manufacturers and exporters of ICU care injections and emergency care injections.
Following the stringent quality control standards, our products are accepted and recommended worldwide.
What is the Working of Hydrocortisone Injection?
It mimics the natural hormone. It suppresses the immune overactivity.
It inhibits inflammatory chemicals. It has rapid action.
It effectively controls redness, swelling, or allergy in the body.
Why Hydrocortisone Injection Side Effects?
When used for short-term, it exhibits mild, tolerable effects.
- • Headache
- • Weight gain
- • Increased appetite
- • Nausea
- • Insomnia
- • Fluid retention
- • Mood swings
What Are Hydrocortisone Injection Severe Effects?
For long-term use, it affects body hormone secretions. It overly suppresses the immune system.
- • Infections – Hydrocortisone reduces immunity. It increases bacterial or other infections.
- • Inhibit Adrenal Secretions – It mimics the body’s hormone. It stops natural secretions. It can cause adrenal insufficiency.
- • Cushing Syndrome – It causes abnormal fat distribution. It leads to extra weight in the face and stomach.
- • Heart Problems – It causes high BP, slow heartbeat, and edema.
- • Stomach Issues – It increases the risk of GIT bleeding. It should be avoided with NSAIDS.
- • Bone Loss – It weakens bones. It inhibits bone formation.
- • Increased Sugar Level – It inhibits glucose digestion.
- • Mood Changes – It interferes with stress hormones.
- • Eye Issue – It can cause glaucoma or cataract.
What Precautions Are Needed for Hydrocortisone Injection Use?
Hydrocortisone has rapid and strong immune effects.
It should be used carefully in children and the elderly.
To be used cautiously in –
- • Pre-existing infections
- • Hormonal disorders
- • Diabetics
- • Thyroid dysfunctions
- • Heart diseases
- • Neurological disorders
- • Musculoskeletal disorders – myasthenia gravis, osteoporosis
- • Eye disorders
- • Pregnant and breastfeeding women
- • Brain injury
- • Geriatric patients
Warnings for Hydrocortisone Use
Abrupt withdrawal after long-term use causes adrenal crisis.
To be used under medical supervision.
- • It should not be used in drug allergy or sensitivity
- • In systemic fungal infections
- • Not for intrathecal or epidural use
- • Avoid live vaccines
- • Avoid IM use in risk of bleeding
Which Drugs to Be Avoided With Hydrocortisone?
Drugs that affect concentration (increase levels):
- • Anti-biotic
- • Anti-fungal
- • HIV medicines
- • Anticonvulsants
The drugs that increase side effects:
- • NSAID
- • Diuretics
- • Neuromuscular blocking agents
Hydrocortisone interferes with other drugs’ action:
- • Anti-coagulants
- • Diabetes medications
- • Live vaccines
- • Mifepristone
- • Anticholinesterases
Important Monitoring Considerations
Long-term use of Hydrocortisone injection should be monitored for:
- • Glycemic index
- • Electrolyte balance
- • Risk of infections
- • Blood pressure
- • Neurological functions
- • Dose management in trauma, surgery
- • Injection site – injury
How to Use Hydrocortisone Injection?
To be administered through the IV or IM route.
Benzyl alcohol should not be used as a diluent.
How to Store Hydrocortisone Injection?
The unconstituted form can be stored at normal room temperature.
The solution made should be stored at refrigerator temperature (2-8°C).
The solution is to be used within a day (24 hours).
Avoid light or moisture.
Conclusion
Hydrocortisone Injection as Hyaxis is widely used in Emergency care settings.
It is used to treat allergies or acute medical conditions.
- • It has a rapid onset of action.
- • It has fast elimination.
