Ketoconazole Tablets
Ketoconazole Tablets
Classification: Antifungal Medicine
Why Ketoconazole Tablets?
It is used for the treatment of several infections caused by yeast and fungi.
It is used orally and is also available as creams for topical use.
Ketoconazole Uses
- • It is used for fungal infections in bones and skin.
- • Valley fever
- • Respiratory fungal infections
- • Fungal Infection in the lungs
- • Yeast skin infections
Why Apraketo 200mg?
Apraketo is an antifungal medicine widely prescribed for fungal infections of the skin and the nails.
Apraketo 200mg is a global standard antifungal medicine, highly effective against systemic fungal infections.
Aprazer Healthcare – The Antifungal Drug Manufacturers and Exporters
Aprazer Healthcare is the largest manufacturer of anti-fungal medicine in India and is also the largest ketoconazole medicine to countries like Ghana, Indonesia, and Nairobi.
We are the top Indian pharmaceutical exporter, developing the top quality advanced fungal care medicines and exporting worldwide to Africa, Southeast Asia, and South America.
How does Ketoconazole Work?
- • It inhibits the formation of the cell wall.
- • It destroys the cell wall component and causes cell death.
Common Side-Effects
The ketoconazole affects cells in the stomach, causes GIT irritation.
- • Skin rashes
- • Irregular heartbeats
- • Abdominal pain
- • Loss of appetite
- • Dark urine
- • Fatigue
- • Diarrhea
Serious Side Effects
Ketoconazole inhibits hormonal secretions and also shows some serious drug interactions.
These are dose-dependent side effects that occur at high doses or long-term use.
- • Severe liver toxicity – jaundice, pale urine, and stool
- • Adrenal insufficiency
- • Arrhythmia
- • QT prolongation
- • Decrease in testosterone levels
- • Reduce sexual ability
Warnings
To be used after a doctor’s prescription only.
Not to be used in patients –
- • Hypersensitive to the drug
- • Mothers breastfeeding infants and children
- • Pregnant women
Precautions for Ketoconazole Use
It should be used cautiously in patients with:
- • Adrenal problems
- • Alcohol use
- • History of irregular heartbeat
- • Liver disease
- • Achlorhydria
Important Monitoring Information
Long-term ketoconazole therapy should be monitored for:
- • Liver function
- • Cardiac rhythms
- • Hormonal functions
General Instructions
- • Do not skip doses
- • Take after food, at the same time
- • Avoid antacids while taking ketoconazole (inhibits absorption)
Drug Interactions
Ketoconazole inhibits the breakdown of several other drugs, increasing the risk of toxicity.
Ketoconazole should be used with extreme caution with:
- • Anti-cholesterol drugs
- • Anticoagulants
- • Cardiovascular drugs
- • Antihypertensive
- • Immunosuppressant
- • HIV medicines
- • Antipsychotics
Conclusion
Ketoconazole is used for fungal infections in cases where other treatments are unable to affect or respond.
It should be used on a doctor’s advice only and monitored for severe complications.
Ketoconazole needs stomach acid to get absorbed.
Antacids inhibit its activity.
