Lamivudine Tablets

Classification – HIV Antiviral

Lamivudine Tablets?

Lamivudine tablets are the medicines used as antivirals. It is widely used in Hep B and HIV treatments. It is used with other drugs to treat and manage advanced Hep B and HIV cases.

Uses of Lamivudine Tablets:

  • • HIV treatment
  • • Hepatitis B treatment
  • • Used in the prophylaxis of HIV exposure.

What is Lamipure 150mg?

It is widely used in hepatic care treatments for Hepatitis B and for HIV care. Lamipure 150mg is commonly used in combination with many other drugs to treat chronic conditions.

Aprazer Healthcare- The Leadership in Anti-viral Therapies

Aprazer Healthcare is the leading manufacturer of advanced antiviral treatment medicines. Manufacturing a range of direct–acting anti-viral and anti-retroviral, we are the top HIV medicine manufacturer and exporter.

We are the top Hepatitis and HIV medicine exporter to countries in Africa and Asia.

Our Antiviral portfolio includes:

  • • Hepatitis B medicines
  • • Hepatitis C medicines
  • • HIV medicine
  • • Influenza medicines.

Lamivudine (Lamipure 150mg) Benefits:

Lamivudine lowering the viral number, also supports liver and immune system of the body.

  • • It lowers the viral load to a large extent.
  • • It improves the immune system.
  • • It improves the quality of life.
  • • Supports liver functions.
  • • It lowers transmission risk.
  • • It lowers the risk of the formation of advanced disease.

Mode of action: Lamivudine

Lamivudine has a selective antiviral action.

It copies the natural DNA bases and stops viral DNA formation.

It stops the chain formation or elongation of the chain, and it terminates the formation of DNA.

Common Side Effects of Lamivudine

The side effects are caused due to systemic absorption, which starts a number of responses.

These are caused at the start of the treatment and then, upon long–term use, settle down.

  • • Head pain
  • • Diarrhea
  • • Weakness
  • • Cough
  • • Running nose
  • • Allergies

Lamivudine: Serious Side Effects

The very serious side effects are caused very rarely due to the effect of the drug on cellular and mitochondrial effects.

  • • Lactic acid builds up in the blood.
  • • Inflammation in the pancreas.
  • • Over-reacting immune system.
  • • It can cause a hepatitis B flare-up.

Precautions for Lamivudine

The treatment with lamivudine should not be stopped immediately, as it can cause reactivation of the virus.

It should be carefully used in people with:

  • • HIV – HBV co-infections.
  • • Liver Problems
  • • Having chronic infections
  • • Kidney disorders

People having lamivudine treatment should avoid alcohol.

Cautiously use, OTC preparation.

It should be avoided to take any risk of physical activity, like operating machinery.

It is not advised for women who feed the infants.

It should be used with care in pregnant women.

Use proper contraception during treatment.

Lamivudine: Warning

It should be used only when prescribed by a doctor.

It should not be used in cases of allergy to the drug.

Monitoring consideration

It should be monitored for:

Lactic acid formation

Liver fat or enlargement

Hepatitis reactivation

Look out for signs of severe gastric effects.

Regular checkup for viral load.

Checking CD4 count.

Drug Interactions

Lamivudine shows drug interactions with:

Ribavirin – It increases the buildup of acid in the blood.

Trimethoprim and Sulfa Drugs – It increases the risk of renal toxicity.

Weight loss medications – They reduce anti-viral efficacy.

It should not be given with sorbitol-containing medicines or oral syrups.

It should not be combined with other antiviral therapies.

Conclusion

It should be used cautiously to treat HIV and Hepatitis. It offers better management and control. It does not offer a cure for the viral infection.

Lamivudine or HIV and hepatitis B treatment is often a lifelong treatment that lowers and keeps the virus under control and unable to be detected.