Tenofovir Disoproxil Fumarate Tablets
Aprazer Healthcare – Leading WHO-GMP certified manufacturer and global exporter of Tenofovir Disoproxil Fumarate Tablets (Tudobest). High-quality, reliable, affordable medicine.
Available finished formulation under our brand name Tudobest.
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Comprehensive Medical Overview
Tenofovir Disoproxil Fumarate
Classification: Antiviral/antiretroviral drug
What is Tenofovir disoproxil fumarate?
It is an antiretroviral drug used for Hepatitis B and HIV treatment.
Tudobest is tenofovir disoproxil fumarate, manufactured by Aprazer Healthcare.
Aprazer Healthcare is a recognized Hepatitis B medicine manufacturer.
We are a generic drug manufacturer, exporting drugs worldwide.
As a Hepatology drug manufacturer, our portfolio spans Hepatitis B medicines and Hepatitis C medicines.
We have a robust distribution network committed to timely supply and reliable delivery of products.
What is tenofovir disoproxil fumarate tablet used for?
• Chronic Hepatitis B treatment
• Pre-exposure prophylaxis for HIV, combined with other antiretrovirals
• HIV infection in combination with other antiretrovirals
Mechanism of action of tenofovir disoproxil fumarate:
It gets incorporated into the DNA chain.
It inhibits DNA chain elongation.
It stops the multiplication /replication of the virus.
Tenofovir disoproxil fumarate side effects include -
• Nausea
• Diarrhea
• Headache
• Fatigue
• Dizziness
Serious side effects include -
• Kidney damage or kidney impairment
• Reduced bone mineral density
• Lactic acidosis
• Severe hepatitis B flare after discontinuation of medicine in chronic hepatitis B.
Precautions that must be followed while using tenofovir disoproxil fumarate:
Patient must be screened for HIV infection before using TDF for Hepatitis B.
TDF cannot be used alone for HIV treatment.
Avoid abruptly stopping or missing the medication.
The conditions that require extreme caution-
• pre-existing kidney disorders
• osteoporosis /bone disorder
• hepatitis B co-infections
• advanced liver disorder
The medicines that require cautious use with TDF:
Concomitant use of NSAIDs or other nephrotoxic drugs with TDF may increase the risk of renal toxicity.
Ledipasvir/Sofosbuvir with TDF requires extreme caution; it must be monitored for renal toxicity.
TDF must not be combined with other drugs containing tenofovir alafenamide as a component.
What are the warnings with the use of tenofovir disoproxil fumarate?
It must not be used in conditions of allergy to the drug.
Liver function must be strictly monitored, as stopping the drug may cause a hepatitis B flare.
It must only be used in combination with other antiretroviral drugs for HIV treatment.
The drug use must be monitored for signs of lactic acidosis and severe hepatomegaly.
The tenofovir disoproxil fumarate dose must be adjusted or avoided in people with kidney disorders.
Alcohol must not be used during the treatment, as it may increase the risk of liver damage.
Didanosine is not recommended to be used with tenofovir disoproxil fumarate.
FAQ
Frequently Asked Questions
Can TDF permanently cure HIV or Hepatitis B?
It cannot cure the disease.
It suppresses the viral count and helps long-term disease management.
Why is stopping the medicine on your own not safe?
Abruptly stopping the medication can lead to viral reactivation.
Why must one limit alcohol intake with tenofovir disoproxil fumarate therapy?
The two do not interact with each other.
However, alcohol may worsen the liver side effects and must be avoided.
Has tenofovir disoproxil fumarate increased my weight?
It usually does not cause weight gain.
The weight increase may be associated with health recovery or some other issues.
Unusual weight changes must be reported to the doctor.
Can tenofovir disoproxil fumarate be given in pregnancy?
Yes, it can be used in pregnancy if prescribed by the medical practitioner.
Who is the hepatitis drug manufacturer from India?
Aprazer Healthcare is a hepatitis medicine manufacturer.