Thalidomide Capsules

Thalidomide Capsules

Classification – Anticancer medicine

What Are Thalidomide Capsules?

It is a cancer medicine. It is used to treat myeloma.
It is an immunomodulatory drug. It is used to treat leprosy.

What Are the Thalidomide Capsules’ Uses?

Thalidomide has multiple actions. It has anti-inflammatory and anticancer properties.

It is widely used for bone marrow cancers.

Multiple Myeloma- Thalidomide is combined with other steroids (Dexamethasone).

It prevents the formation of new blood vessels.

It causes starvation of cancer cells.

Type-2 Lepra Infection – It is an autoimmune condition like leprosy.

It prevents inflammatory complications.

It is used to reduce severe painful skin lesions.

Off–label Uses

• •  Breast cancer
• •  Kaposi Sarcoma
• •  Glioblastoma

What Are Thalinew Capsules?

Thalinew, manufactured by Aprazer Healthcare, is the highest quality thalidomide capsules.
Thalidomide is used worldwide to treat severe, painful skin lesions associated with leprosy.
It is available in Africa, South America, and Southeast Asia.

Aprazer Healthcare – The Leadership in Anticancer Drug Manufacturing

Aprazer is a globally renowned oncology medicine manufacturer.
Having oncology solid oral plants and plants for manufacturing injectable, we are the top oncology oral manufacturer and the top oncology injectable manufacturer.
Expanding our reach worldwide, Aprazer Healthcare has positioned itself as India’s top quality oncology oral exporter.
Our product catalogue includes a diverse range of generic anticancer medicines and injections.

• •  Chemotherapy medicines
• •  Targeted therapy medicines
• •  Hormone therapy medicines

What is the Working of Thalidomide Capsules?

Thalidomide has multifaceted actions-

• •  Immunomodulation
• •  Anticancer
• •  Anti-inflammatory

It inhibits the process of angiogenesis. It stops the formation of new blood vessels in cancer cells.
It causes cancer cells to starve and die.
It suppresses the immune system. It inhibits the inflammation-induced pain and skin lesions.

What Are the Thalidomide Capsule Side Effects?

The side effects occur at the start of the treatment. It settles down with a dose adjustment.

• •  Drowsiness
• •  Skin rash and itchiness
• •  Anxiety, confusion
• •  Black tarry stool
• •  Cough, dry mouth
• •  Irregular heartbeat
• •  Fever, chills
• •  Loss of appetite, taste
• •  Muscle weakness
• •  Numbness in hands, fingertips, feet
• •  Abdominal pain
• •  Chest pain, trouble breathing
• •  Blurred vision

What Are Thalidomide Serious Side Effects?

It can cause severe, permanent side effects –

• •  Clot formation
• •  Nerve damage in limbs
• •  Severe birth defects

Other side effects, which are dose dependent, include-

• •  Liver toxicity
• •  Bone marrow suppression
• •  Hypo-thyroidism

Why Use Thalidomide Capsules Cautiously?

It causes a severe birth defect.
It can lead to permanent nerve damage. It causes changes in blood count.
To be used cautiously in patients with –

• •  Nerve disorders
• •  Blood clotting disorder
• •  Heart disorders
• •  Liver disorders
• •  Kidney disorders
• •  Blood disorders

When Not to Use Thalidomide Capsules?

To be used under prescription.
Avoid in cases of drug allergies.
Avoid its use by mothers feeding infants.
Avoid in Pregnant women. It causes severe birth defects.

Why Does Thalidomide Require Regular Monitoring?

Thalidomide can cause severe, irreversible side effects.
It causes birth disorders.
It requires regular monitoring and dose adjustments.
The long-term therapy should be checked for

• •  Early signs of neuropathy
• •  Neurological functioning
• •  Blood count
• •  Heart functions
• •  Thyroid functions
• •  Signs of skin reaction

Conclusion

Thalidomide is used in various cancers.
It should be used cautiously with special consideration.
It causes birth defects.