Ursodeoxycholic Acid SR Tablets

Ursodeoxycholic Acid SR Tablets

Classification: Hepatoprotective Medicine

What Are Ursodeoxycholic Acid SR Tablets?

It is an analogue of the bile acid.

It is a sustained-release tablet. It has prolonged effects.

It performs the bile acid functions and is protective in nature.

What Are Ursodeoxycholic Acid SR Tablet Uses?

• Primary Biliary Cholangitis Disease – It is an autoimmune condition. It destroys the small bile ducts.
• The body is unable to produce enough bile acid.
• It accumulated toxins in the liver.
• Ursodeoxycholic acid improves bile acid secretion.

• Cholesterol-induced Gallstones – It is widely used to dissolve gallstones.
• It is widely used to dissolve non-calcium stones.
• It reduces the absorption and formation of cholesterol.
• It reduces the cholesterol content in bile acids. It then leads to the dissolution of cholesterol stones.
• Cholestasis Disease of the Liver – In this, the flow of bile acids is blocked.
• The toxic bile juice builds up in the liver.
• Ursodeoxycholic acid is used to –
  • • Replace the toxic bile acid with a less toxic content.
  • • Improve the flow of bile.
  • • Alter the toxic bile acid pool.
• Cystic Fibrosis – It is the production of thick bile. The bile is mucus-laden. It clogs the ducts and the flow. The ursodeoxycholic acid reduces the thickness.
• It increases water and bicarbonate ion secretion into the bile.
• It increases its fluidity and opens the clogged bile acid points.

What Are Udikast SR Tablets?

Udikast SR is, ursodeoxycholic acid tablet, manufactured by Aprazer Healthcare.

It is a sustained-release medicine to bring a prolonged effect.

It is used as a natural analogue of bile acid.

Udikast SR is widely used to prevent liver damage and delay disease progression.

Aprazer Healthcare – A Name in Gastrointestinal and Hepatic Care

Aprazer is a pharmaceutical manufacturing company.

We are the top gastroenterology medicine manufacturers and exporters.

Our product catalogue for GIT and Hepatic care includes-

• • Hepatoprotective medicines – Udikast SR, Udikast – 300mg
• • Gastro-selective antibiotic – Rifaxigem
• • Nutritional supplements – Hepakast (3 essential amino acids).

Present globally, we are recognized as the top gastroenterology medicine exporters from India.

What is the Working of the Ursodeoxycholic Acid SR Tablet?

It reduces cholesterol in bile acids. It replaces toxic components in the bile juice.

It improves the flow of bile acid. Improves its drainage and helps the secretion of less toxic bile acids.

What Are Ursodeoxycholic Acid SR Tablet Side Effects?

It causes mild, temporary gastrointestinal side effects.

Due to increased bile flow, it effects git motility and causes –

• • Diarrhea
• • Abdominal pain
• • Irritation in the intestine
• • Bloating, gas
• • Nausea

Very rarely, it causes systemic side-effects –

• • Dizziness
• • Headache
• • Skin rashes
• • Inflammatory effects
• • Immune responses – flu-like syndromes
• • Back pain
• • Hair loss

What Are Ursodeoxycholic Acid SR Tablet Serious Side–Effects?

The severe effects are caused by excessive doses.

It can be caused by an allergy to the drug.

It can exacerbate serious effects in advanced liver disorders.

It can worsen the liver dysfunctions.

It can accumulate and cause toxicity.

It is reduced to a toxic component in the colon.

Why Use Ursodeoxycholic Acid Carefully?

It should be monitored to prevent –

• • Toxicity
• • Worsening of liver functions

It can dissolve gallstones made up of cholesterol.

It cannot dissolve calcium gallstones.

It should be used cautiously in –

• • Pregnant ladies
• • Breastfeeding mothers
• • Avoid pregnancy during therapy
• • Advanced liver diseases

What Are the Important Warnings for Ursodeoxycholic Acid Use?

To be used under medical prescription.

It should not be used in end-stage liver disease.

It must be avoided in peptic ulcers. It can irritate.

It cannot be used in the condition of bile duct obstruction.

It cannot dissolve calcified gallstones.

Avoid in severe cases like –

• • Infection in the gall bladder.
• • Non-functioning gall bladder.
• • Allergy to the drug.

Why Monitor Liver Function With Ursodeoxycholic Acid Therapy?

Long-term use is recommended to monitor liver function to prevent –

• • Toxicity
• • The decline in liver functions
• • High dose risks
• • Metabolite accumulation

What Medicines May Affect Ursodeoxycholic Acid Absorption?

• • Antacids containing aluminum
• • Oral contraceptives
• • Lipid-lowering drugs
• • Drugs binding with bile acid
• • Increases the absorption of cyclosporine
• • Lowers the efficacy of heart medicines