💊 Anthelmintics
S.No.Dosage FormCompositionDomestic MarketExport MarketAction
281TabletsIvermectin 3/6/12/18/20/24/30 mgYesYes
282TabletsNiclosamide 500 mgYesYes
283TabletsPraziquantel 600 mgYesYes

Anthelmintic Drugs

These treat infections caused by worms.

It includes the infections caused by –

  • • Round worms
  • • Tapeworms
  • • Flukes
  • • Hookworms

Why is Helminthic Infection Caused?

It is causes through contaminated soil and water.

Ingesting foul food or water.

Enter through the skin by soil or water.

What Are Helminthic Infection Symptoms?

The symptoms depend on the burden of worms in the body.

Mild infection may be asymptomatic.

A higher count of worms may cause-

  • • Abdominal pain
  • • Diarrhea
  • • Nausea
  • • Loss of appetite
  • • Fatigue
  • • Anemia
  • • Worm in the stool

If the infection is caused in the lung, it causes cough, wheezing.

It can cause respiratory side effects. Shortness of breath.

Skin infections can cause skin rashes, pruritus.

In rare cases, the worms can affect the brain.

Worms can cause liver dysfunction, inflammation.

The Anthelmintic Drugs Which Are Used Commonly

Ivermectin Tablets - It is widely used to treat infections caused due to lice, mites, and worms.

It is used in river blindness to reduce skin rash.

It is used to treat intestinal threadworms.

It is used to treat skin lesions associated caused by Rosacea

It is used topically to treat head lice.

Praziquantel Tablets - It is used to treat infection by the flukes and the tapeworms.

It is used to treat skin infections caused by schistosomes.

It is used to treat lung infections caused by fluke worms.

It is used in stomach infections caused by flukes.

Niclosamide Tablets -These are effective in tapeworm infections.

The tape worms cause intestinal infections.

They are killed. The death tapeworm is passed in the stool.

What is an Anthelmintic Drug Working?

These drugs permeate the cell membrane. They cause-

  • • Cell paralysis
  • • Disrupts the formation of microtubules.
  • • Severe muscle contractions.
  • • Disrupts the energy production in the parasites.

What Can Be Anthelmintic Drug Side-effects?

The most common side effects include-

  • • Loss of appetite
  • • Muscle pain
  • • Fever

GIT Side-effects

  • • Abdominal pain
  • • Vomiting
  • • Cramps in the stomach

Neurological Effects

  • • Headache
  • • Dizziness
  • • Fatigue

Skin Side-effects

  • • Rashes
  • • Itching
  • • Purities

What Are Anthelmintic Drug Severe Side Effects?

Liver Dysfunction

Drugs like albendazole elevate liver enzymes.

It reduces the blood count.

The killing of the parasites can cause an immune response.

It can cause dead worm accumulation.

It can cause toxicity. It may lead to seizures.

Which is the Anthelmintic Drug Manufacturer in India?

Aprazer Healthcare manufactures a complete range of pharmaceutical products.

Aprazer Healthcare is the leading pharmaceutical manufacturing company from India.

We manufacture a range of drugs for infectious conditions.

  • • Anthelmintic
  • • Antifungal drugs
  • • Antibiotics
  • • Antiprotozoal drugs

We are the top drug exporters from India.

Trusted across borders, we lead the way in anthelmintic drug export to countries in Africa, South America, and Southeast Asia.


FAQ

Are Anthelminthic Drugs for OTC Use?

• The broad-spectrum anthelmintic drugs require a prescription.
Example – Ivermectin, Praziquantel
• The drugs for common pinworms are available as OTC.
Example – Albendazole, Mebendazole

How Long to Use Anthelmintic Drugs?

• It depends upon the type of infection.
• It is generally a short-duration course.

Can We Use an Anthelmintic in Pregnancy?

• They are contraindicated in pregnancy.
• They should be used when asked by a doctor.

When Not to Use Anthelmintic Drugs?

It should not be used in-
• Allergy to the drug
• Pregnant / breastfeeding women
• It should be used cautiously in patients with other medical conditions.
• Praziquantal should not be infections of the eye or spinal cord.