Anti-Fungal Products

Anti-Fungal Products

Antifungal products are widely used to treat fungal infections.

These are used to treat systemic infections.

They are used topically for skin, nail, or scalp infections.

These are available in the form of –

• • Antifungal tablets
• • Antifungal capsules
• • Antifungal powders
• • Antifungal lotions
• • Vaginal suppositories
• • Antifungal shampoos

How Are Fungal Infections Caused?

Fungal infections are caused by coming into contact with -

• • Contaminated surfaces
• • Inhalation of spores
• • Skin injuries

Fungal cells grow in moisture and humidity.

They grow in wet areas. They are widely found in moisture-trapped regions.

The fungal infection is widespread between toes, fingers, and armpits that remain wet and moist.

The groin areas that are not dried may lead to infection.

The Uses of Antifungal Drugs

Antifungal drugs are used to treat a wide variety of infections caused by molds and yeast.

These are widely used to treat-

• • Superficial infections of the skin.
• • Systemic infections in the lungs, bloodstream, and spinal cord.

Athlete’s Foot – Fungal infection in the feet, between the toes.

Fungal infections in the –

• • Scalp
• • Groin or thigh areas
• • Nails
• • Oral fungal infections
• • Vaginal infections
• • Skin fungal infections

The Antifungal Drug Types

Azoles – They inhibit ergosterol synthesis. It is widely used for cell membrane formation.

These treat skin, nail, or vaginal infections.

It includes-

• • Ketoconazole
• • Clotrimazole
• • Fluconazole
• • Itraconazole

Polyenes – They include drugs like –

• • Amphotericin B
• • Nystatin
• • Natamycin

It is used to treat infections in the mucosal layer.

• • Oral infections
• • Eye infections

Allylamines- They include drugs like-

• • Terbinafine
• • Naftifine

They are used to treat dermatological infections.

• • Athletic foot
• • Ringworm infection

Echinocandins- These are used in severe fungal infections.

They are usually given as IV therapy.

These are used to treat-

• • Yeast infection in the blood
• • Mold infection in the lungs

Other Miscellaneous Types

Other drugs include antimetabolites like Flucytosine. It is widely used for internal infections.

It is used in brain/ spinal cord infections.

Grisofulvin – for superficial infections.

It is used in skin/nail/hair infections.

The Antifungal Drugs That Are Widely Used

• • Itraconazole
• • Ketoconazole
• • Posaconazole
• • Terbinafine
• • Voriconazole

How Do Antifungal Drugs Work?

The drugs for fungal infection are either-

The fungicidal drug – They kill the fungal cells.

Fungistatic drugs – They inhibit further spread of the fungal cells.

They work by destroying the cell membrane.

It causes the cell organelle to leak.

They also inhibit nucleic acid synthesis.

What Are the Anti-fungal Drug Side Effects?

It causes mild side effects. The long-term systemic use can cause severe side effects.

• • Abdominal pain
• • Nausea
• • Vomiting
• • Indigestion
• • Skin irritation
• • Rashes
• • Increased photosensitivity
• • Headache
• • Dizziness

It causes rare systemic side-effects –

• • Liver toxicity
• • Disrupt the hormonal cycle
• • Distort metabolism

Which is the Leading Indian Pharma Company Manufacturing Antifungal Products?

Aprazer Healthcare is the top Indian pharmaceutical company.

Manufacturing the global standard medicines, we are ranked as the top drug exporters from India.

We manufacture a comprehensive range of pharmaceutical products.

We are known worldwide for manufacturing quality, efficient products.

We are the exporter of drugs to global markets.

We are the largest pharmaceutical drug exporter to South Africa, South America, and Southeast Asia.

Conclusion

Antifungal drugs are available as over-the-counter drugs. These are widely used for topical or superficial infections.

The oral antifungal medicines should be used upon a doctor’s prescription.