Immunosuppressive Agents
| S.No. | Dosage Form | Composition | Domestic Market | Export Market | Action |
|---|---|---|---|---|---|
| 240 | Tablets | Azathioprine 25/50/100 mg | Yes | Yes | |
| 241 | Capsules | Cyclosporine 25/50/100 mg | Yes | Yes | |
| 242 | Tablets | Methotrexate 2.5/5/7.5/10/15 mg | Yes | Yes | |
| 243 | Tablets | Mycophenolate Mofetil 250/500 mg | Yes | Yes | |
| 244 | Tablets | Mycophenolate Sodium 180/360 mg | Yes | Yes | |
| 245 | Tablets | Pidotimod 400 mg | Yes | Yes | |
| 246 | Tablets | Sirolimus 0.5/1/2/3 mg | Yes | Yes | |
| 247 | Tablets | Tofacitinib 5 mg/11 mg (ER) | Yes | Yes |
Immunosuppressive Agents
Immunosuppressive agents are used to reduce the immune activity.
These drugs prevent the body from attacking its own organs.
They are used to prevent organ rejection.
What is the Overactive Immune System?
It is a condition in which the body attacks itself.
The body reacts to foreign substances.
In the overactive system, the body reacts to harmless components.
It induces a flare, an allergic reaction.
It leads to an immune response.
What Are the Immunosuppressive Agents’ Uses?
It lowers the immunity.
It is used to control autoimmune functions.
- • Lupus
- • Rheumatoid arthritis
- • Multiple sclerosis
- • Severe IBS and colitis
- • Allergy
- • Aplastic anemia
What is the Working of Immunosuppressive Agents?
It inhibits T-B cell signaling.
It blocks the proliferation of immune cells.
It reduces the inflammatory signals.
It stops the overactive immune system.
Why Use Immunosuppressive Agents Used in Organ Transplantation?
They prevent rejection in organ transplants.
It prevents the graft.
It suppresses the immune system, attacking the new organ.
It reduces the acute immune episodes.
What Are the Side Effects of Immunosuppressive Agents?
They reduce the immune response of the body.
It increases -
- • Risk of infection.
- • Risk of cancer.
The Common Side Effects Include –
- • High blood pressure
- • High sugar levels
- • Increase in cholesterol
- • Weight gain
- • Kidney dysfunctions
- • GIT side effects
- • Thinning of bones
It leads to neurological side effects.
- • Headaches
- • Difficulty in sleeping
- • Anxiety
- • Delayed wound healing
Who Should Be Careful in Using Immunosuppressive Agents?
It should not be used in pregnancy.
Avoid using alcohol with immunosuppressive agents.
It causes drug interaction.
It should be used carefully in people with other medical conditions.
- • Heart disease
- • Hypertension
- • Active infections
- • Avoid using live vaccines.
It can interact with other drugs like -
- • Antibiotics
- • Antifungals
- • Anti-seizure
- • Anti-TB
Which Are Immunosuppressive Medicines?
- • Azathioprine tablets
- • Cyclosporine capsules
- • Methotrexate tablets
- • Mycophenolate Mofetil tablets
- • Mycophenolate Sodium tablets
- • Sirolimus tablets
- • Tofacitinib tablets
Which is the Largest Immunosuppressive Medicine Manufacturer?
Aprazer Healthcare is the leading Indian drug manufacturer and exporter.
We manufacture high-quality pharmaceutical products.
As the leading nephrology medicine manufacturer, we manufacture immunosuppressants widely used in kidney transplants.
Present globally, we are the largest drug exporters worldwide.
We export immunosuppressive medicines to countries in Africa, Asia, and South America.
We manufacture a complete range of immunosuppressive medicines.
Conclusion
The immunosuppressive drugs lower the immunity.
It greatly increases the risk of infections.
One should cautiously maintain hygiene.
Avoid eating raw meat, uncooked food.
Avoid unusual contact with infected people.
Practice safe sex.
FAQ
What Can Be an Autoimmune Disease?
It includes –
• Rheumatoid arthritis
• Lupus
• Multiple sclerosis
Enlist the Immunosuppressive Agent Used in Cancer Therapy?
• Methotrexate tablets
Which is the Widely Used Medicine in a Kidney Transplant?
• Mycophenolate Sodium – Myfocept S 360
Which is the Top Quality Immunosuppressant Used in Arthritis?
It inhibits the damage to the joint.
It reduces-
• Inflammation
• Stiffness and pain in the joints
• It reduces swelling
Why Should One Not Stop Immunosuppressive Therapy on Its Own?
• Disease flare-up
• Acute organ rejection in organ transplantation therapy
• Withdrawal symptoms
• Leads to drug resistance
Pidotimod Prevents the Recurrence of UTI. Why?
It prevents recurrence of infection in-
• UTI
• Respiratory infection
