Nephrology & Diuretics

Nephrology and Diuretics

Nephrology medicines are the medicines used to treat kidney disorders.

The impaired kidney functions lead to infiltration of blood and fluid through the kidney.

• • It leads to the accumulation of fluid.
• • It reduces the absorption of minerals.
• • It causes an electrolyte imbalance
• • Buildup of toxins
• • Injury to the nephrons

Aprazer Healthcare – The Top Quality Nephrology Medicines

Aprazer Healthcare is India’s leading nephrology medicine manufacturer.

Leveraging the advanced technology and the top-quality equipment, we are capable of manufacturing bulk quantities with efficient quality.

We manufacture the widest range of affordable kidney dysfunction medicines.

Our products available worldwide are ranked as the top quality nephrology medicines.

Our product portfolio includes a comprehensive range of nephrology drugs.

• • Transplant medicines
• • Urinary retention medicines
• • Antispasmodic medicines
• • Prostatic hyperplasia (BPH) medicines

As the leading manufacturer in India, Aprazer Healthcare is the top nephrology drug exporter.

We are the leading exporters of antihypertensive drugs, diuretics, and immunosuppressants.

The Top-quality Nephrology Medicines Manufactured by Aprazer Healthcare

• • Bethanechol Chloride Tablets – Bethkast
  It is a widely used medicine for urinary retention.
• • Tacrolimus Tablets – X-Graf
  It is the immunosuppressant used in organ transplants.

The Top-quality Diuretics Include

• • Torsemide tablets
• • Torsemide and spironolactone tablets
• • Furosemide and spironolactone tablets

What Are Diuretics and Their Function?

These are also called water pills.

These medicines eliminate excess salt and water in the form of urine.

They reduce the blood volume. It excretes fluid.

It reduces blood pressure. It reduces the extra fluid accumulation in the body.

The Uses of Diuretics

Diuretics are widely used in -

• • High blood pressure – They reduce the volume of fluid in the blood. It reduces pressure on the walls.
• • Kidney disease – It is widely used in kidney disorders. It filters out sodium and extra water.
• • Heart failure – It reduces the accumulation of extra fluid in the heart. It leads to effective pumping of the heart.
• • Liver disease – It is used to clear out accumulated fluid in the abdomen. It is used in advanced liver disorders.
• • Glaucoma – It reduces the fluid production in the eye. It reduces pressure on the optic nerve.
• • Fluid retention – It helps to excrete the accumulated fluid in body tissues and organs.

The Types of Diuretics

Thiazide Diuretic – They lead to the excretion of sodium and chloride. It increases water excretion.

Loop Diuretic – They are strong. It leads to the excretion of sodium, potassium, and chloride ions.

Potassium-sparing Diuretic – They preserve potassium ions. It helps retain potassium levels.

Osmotic Diuretics – They prevent the reabsorption of fluid through the kidneys. It draws water into the renal tubules. It leads to the excretion of water.

Carbonic Anhydrase Inhibitors – It inhibits the absorption of bicarbonate ions. It reduces the accumulation of water. It increases its excretion. It is widely used to reduce aqueous humor secretion in the eye. It is used in glaucoma.

The Common Side Effects of Diuretics

Diuretics increase the urine volume. It expels the extra fluid and water from the body.

It can cause an imbalance in water levels.

It leads to mineral decline in the body.

• • Increased urination
• • Dehydration
• • Low blood pressure
• • Headaches
• • Muscle cramps
• • weakness
• • Gout
• • imbalance of electrolyte levels
• • Sexual dysfunction

What Are the Serious Side Effects of Diuretics?

The diuretics cause changes in electrolyte balance.

The depletion or the increase in minerals and salts causes several effects-

Arrhythmia – The changes in potassium levels in the body. It leads to fluctuation in rhythm.

Extreme Dehydration – It can cause severe fluid depletion. It can lead to hypovolemia. It can severely reduce blood pressure.

Renal Injury – It reduces the fluid excretion. It increases the stress on the kidneys.

Low Sodium Levels – They can cause excess excretion of sodium ions. It leads to neurological side effects. It causes confusion, seizures, coma, etc.

Ototoxicity – The high doses for long-term use lead to hearing loss.

Severe Allergy – It can have an anaphylaxis reaction. It can cause skin rashes. Acute liver injury.

Conclusion

Aprazer Healthcare manufactures an affordable range of nephrology drugs.

Nephrology medicines should be used when prescribed by the healthcare practitioner.