Coliaxis

Coliaxis Injection

Composition – Colistimethate Sodium (1 Million IU)

Classification – Antibiotic Injection used in ICU

What is Coliaxis?

It is a very strong bactericidal, killing many bacteria and is used in severe infections. Coliaxis injection is used in ICUs for resistant bacterial infections.

Benefits of Coliaxis

• • Rapid bactericidal effect.
• • Used in multi-drug resistant infections.
• • Reduce severe endotoxin effects.

Uses of Coliaxis

• • Pneumonia induced by a ventilator
• • Sepsis (Infection in the blood)
• • Urinary Tract Infections
• • Infections of the brain (Meningitis)

How does Coliaxis work?

It leads to cell death by causing holes in the bacterial cell membrane.

The Common Side Effects of Coliaxis

• • Nausea
• • Vomiting
• • Cramps
• • Allergic reactions
• • Renal toxicity
• • Neurological toxicity
• • Visual disturbance

The Severe Side Effects of Coliaxis

• • Severe Renal toxicity
• • Neuromuscular blockade
• • Muscular paralysis

Precautions While Using Coliaxis

To be cautiously used in –

• • Renal disorders
• • Blood disorders
• • Severe illness

Important Considerations for Use

Due to its narrow therapeutic window, it requires careful dose monitoring.

Regularly monitor for –

• • Renal toxicity
• • Neurotoxicity

Contraindications

• • Allergy or hypersensitivity to drug components.
• • Myasthenia Gravis

Drug Interactions

• • Aminoglycosides
• • Other antibiotics
• • NSAIDS or other nephrotoxic drugs
• • Neuromuscular blocking drugs
• • General anesthetic drugs

Warning

To be used under a doctor or medical professional

Administration Instructions

• • It can be administered as IV, nebulization, or the intrathecal route.

Storage

• • Powdered form can be stored at room temperature.
• • The reconstituted solution can be stored at 2-8 degrees Celsius.
• • The reconstituted solution should be used within 24 hours.

Aprazer Healthcare- Affordable Critical Care Medicines

Aprazer Healthcare manufactures top–quality cephalosporin, penicillin, and polymyxin antibiotics, widely used in ICU care.

Why Aprazer Healthcare?

• • We are the leading critical care injection manufacturer and exporter, with remarkable global presence and worldwide availability, we are the leading pharmaceutical exporters.
• • Global Standard Medicines- WHO-GMP certified manufacturing facilities.
• • Assured Quality and Safety – Our stringent quality control measures ensure effective and safe formulations.
• • New Advanced Molecules – With high capital infrastructure, leveraging new technology, we are at the forefront in developing new drugs and innovative therapies.