Description
Description
Dacikast
Composition: Daclatasvir 60mg
Therapeutic Class: Antiviral
Dacikast: Globally Available, Affordable Hepatitis C Medicine
Dacikast is available globally in 50-plus countries and is a well-tolerated, highly prescribed treatment for Hepatitis C.
Aprazer Healthcare: World-class Hepatology Medicines
Aprazer Healthcare manufactures international standard hepatology medicines, WHO-GMP certified, with assured therapeutic efficacy and safety.
What is Dacikast?
Dacikast consists of Daclatasvir, which is a direct-acting antiviral used in combination for chronic Hepatitis C treatment.
Uses of Dacikast
- • Chronic Hepatitis C
- • Against HCV strains 1–3 and others
- • Used in combination therapy
How does Dacikast work?
- • NS5A protein inhibition
- • Inhibits viral replication, assembly, and release
- • Blocks new viral cell formation
Benefits
- • Rapidly reduces viral load
- • Well tolerated, fewer side effects
- • Shorter treatment duration
- • Broad spectrum of activity (genotypes 1–3)
- • Safe in HIV co-infections
- • Can be used in compensated cirrhosis
- • Can be used post-liver transplant
- • Less risk of development of resistance
Common Side Effects
- • Nausea
- • Dizziness
- • Headache
- • Digestive issues
- • Tiredness
- • Diarrhea
Severe Side Effects
- • Severe fall in RBC count when used with Ribavirin
- • Anxiety, confusion
- • Elevated liver enzymes, or hepatic decompensation in advanced-stage liver disorder
- • Low heart rate when used with Amiodarone
Precautions
To be used cautiously in patients with:
- • Heart disorders
- • Decompensated liver cirrhosis
- • HIV co-infections
- • Drug interactions
Contraindications
- • Not to be used if any previous allergy or hypersensitivity to Daclatasvir, or any excipients.
- • Breastfeeding mothers
- • Pregnant women
Warning
It is a prescription drug to be taken under medical supervision only.
Important Safety and Monitoring Information
Regular monitoring of hepatic functions, renal functions, cardiac functions, co-infections
Drug interactions – Ribavarin and Amiodarone
Not to be used as monotherapy for HCV infections.
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