Description
Leucokast-50
Composition: Leucoverin Calcium IP– 50mg /5ml
Supportive Cancer Therapy: Folic acid derivative
Leucokast: Enhancing Therapy, Protecting Health
Leucokast is widely accepted by oncologists worldwide, used as supportive cancer therapy.
It is highly demanded in oncology hospitals, government healthcare settings, and clinics.
Aprazer –A Global Name in Quality Medicines
- • Aprazer Healthcare is the largest oncology medicine manufacturer, develops advanced oncology medicines, and exports worldwide.
- • WHO- GMP certified.
- • Assured therapeutic efficacy and quality.
- • Available in 50+ countries
What is Leucokast?
Leucoksat is an active form of folic acid, widely used in oncology care settings as an adjuvant to chemotherapy, to increase its effectiveness and to reduce side effects.
Uses of Leucokast
- • Colorectal cancer (adjuvant to 5-fluorouracil)
- • Blood cancer, lymphomas, and solid tumors with anti-folate agents
- • To reduce methotrexate, trimethoprim, and pyrimethamine toxicity.
How Does it Work?
- • It restores folate levels lost during anticancer therapy.
- • Increases the anti-cancer activity of fluorouracil medicines.
Common Side Effects
When combined with chemotherapy –
- • Weakness
- • Skin rashes
- • GIT upset
- • Mouth sores
- • Diarrhea
- • Nausea
- • Vomiting
- • Reduced appetite
Serious Side Effects
When combined with other chemotherapy agents
- • Bone marrow suppression
- • Gastrointestinal bleeding
- • Severe Diarrhea
- • Risk of dehydration
- • Dizziness, convulsions, and fainting
- • Shortness of breath
- • Irregular heartbeat
Precautions
- • To be used cautiously in –
- • Renal dysfunctions
- • Vitamin B-12 deficiency
- • Anemia
- • Epilepsy
Contraindications
- • Not to be used if any previous allergy or hypersensitivity to leucoverin or any excipients.
- • Anemic or low RBC count.
- • Breastfeeding mothers
- • Pregnant women
Warnings
To be used under the supervision of a medical practitioner or oncology specialist, having adequate diagnostic and monitoring facilities.
Not to be used as a folate supplement.
Important Safety and Monitoring Information
Regularly monitor blood count, hepatic and neurological assessments, manage infection risks, and assess ocular and renal functions.
Storage
It should be stored at 2-8 degrees Celsius, protected from light.
Administration Instructions
To be administered IV and IM
To be used immediately after reconstitution.
