MITOMYCIN

Mitomycin -10mg

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Description

Description

Mitomycin

Composition: Mitomycin – 10 mg

Classification: Antineoplastic

Proven Efficacy, Global Acceptance

Mitomycin, driven out of proven scientific formula, is widely accepted by world-leading oncologists for affordable and effective anti cancer medicine used against several cancers.

Aprazer: A Trusted Name in Oncology

Aprazer healthcare is the leading name in oncology, manufacturing world-standard anti cancer medicines.
The leading oncology exporter that develops affordable advanced care therapeutics.
It supplies to 50 + countries.
WHO-GMP certified, assured therapeutic efficacy and safety.

What is Mitomycin?

Mitomycin is an anticancer medicine used to treat various cancers.
It is used alone or in combination as a chemotherapy agent .

Uses of Mitomycin

  • • Gastrointestinal cancers
  • • Blood cancer
  • • Breast cancer
  • • Pancreatic cancer
  • • Cancers of the uterus (urinary bladder)

How does it work?

Mitomycin causes cancer cell death by cross-linking DNA strands, inhibiting DNA replication, and multiplication.

Common Side Effects

  • • Nausea
  • • Mouth ulcers
  • • Low blood count
  • • Risk of infections
  • • Diarrhea
  • • Loss of appetite
  • • Weakness
  • • Local tissue necrosis

Serious Side Effects

  • • Pulmonary fibrosis – dry cough, shortness of breath
  • • Renal toxicity – increased creatinine, proteinuria
  • • Hepatic toxicity
  • • Hemolytic uremic syndrome

Precautions

To be cautiously used in:

  • • Renal disorders
  • • Hepatic disorders
  • • People with pulmonary fibrosis or pneumonitis
  • • Elderly patients
  • • Avoid combining with other myelosuppressant drugs
  • • Bleeding disorders
  • • Severe infections

Contraindications

  • • Not to be used if any previous allergy or hypersensitivity to Mitomycin or any excipients.
  • • Breastfeeding mothers
  • • Pregnant women

Warning

To be used under the supervision of a medical practitioner or oncology specialist, having adequate diagnostic and monitoring facilities.

Important Safety and Monitoring Information

Monitor the following regularly:

  • • Total blood count
  • • Renal functions
  • • Pulmonary functions
  • • Hepatic functions

Storage

It should be stored at 2-8 degrees Celsius, protected from light.

Administration Instructions

  • • To be administered as a slow IV infusion.
  • • Avoid IV push or rapid bolus.
  • • To be used immediately after reconstitution.
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