Description
Description
Palbocib – 125
Composition: Palbociclib – 125 mg
Therapeutic Class: Anti-neoplastic
Palbocib: Globally Validated for Efficacy and Safety
Palbocib is widely prescribed by oncologists and is available worldwide.
Aprazer Healthcare: A Global Pharmaceutical Name
Aprazer, a leading pharmaceutical company, manufactures a range of life-saving medicines in various therapeutic segments.
As the largest oncology medicine exporter, it exports anticancer medicines to 50+ countries.
WHO-GMP certified, assured therapeutic efficacy and safety.
What is Palbocib?
It is a targeted therapy drug that is used for:
- • Hormone-positive (HR+) breast cancer
- • HER2-negative and advanced-stage breast cancer
- • It targets genetic mutations of the enzymes like HER2, CDK
Uses of Palbocib
- • HR+ cancer–hormone receptor-positive breast cancer
- • HER2-negative breast cancer
- • Metastatic breast cancer
How does it work?
- • Tyrosine Kinase Inhibitor
- • It inhibits the crucial enzymes and arrests the stage of the cell cycle, inhibiting cell proliferation.
- • Stop multiplication
- • Stops tumor growth
Common Side Effects
- • Low blood count – low neutrophils, low RBC count
- • Loss of appetite
- • Nausea, vomiting
- • Mouth ulcers
- • Tiredness
- • Skin rashes
- • Hair loss
Serious Side Effects
- • Severe fall in neutrophils
- • Fatal lung inflammation – pneumonitis
- • QT prolongation
- • Elevated liver enzymes
- • Opportunistic infections – fungal, bacterial
Precautions
To be used cautiously in patients with:
- • Pre-existing lung disease
- • Liver dysfunction
- • Renal dysfunction
- • Blood disorders
- • Cardiac abnormalities
Contraindications
- • Not to be used if any previous allergy or hypersensitivity to Olaprib or any excipients
- • Breastfeeding mothers
- • Pregnant women
Warning
- • To be used under medical prescription only
Important Safety and Monitoring Information
Regular monitoring of the:
- • Liver function – monitor for elevated liver enzymes
- • Blood count – CBC count
- • Respiratory functions- interstitial lung disease
- • Cardiac functions – QT prolongation
- • Opportunistic infections- fungal, bacterial
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