Sofokast

Sofosbuvir Tablets 400 mg

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Description

Description

Sofokast

Composition: Sofosbuvir – 400mg

Therapeutic Class: Antivirals

Sofokast: Worldwide Access to Affordable Hepatitis C Medicine

Sofokast, manufactured by Aprazer Healthcare, is a WHO-listed essential medicine for hepatitis C.

Aprazer Healthcare is a globally trusted name in hepatology medicine manufacturing, developing advanced treatments for both hepatitis C and B.

WHO-GMP certified, assuring therapeutic efficacy and safety.

What is Sofokast?

An antiviral against HCV, used in combination for the treatment of Chronic Hepatitis C.

Uses of Sofokast

  • • Chronic Hepatitis C
  • • HCV-HIV co-infections

How does it work?

It inhibits the viral DNA synthesis, it is a prod rug drug which is activated in the liver.

Benefits

  • • Can be used in cirrhosis (compensated /decompensated)
  • • HIV co-infections
  • • In children> 3 years
  • • Post liver transplant
  • • Effective across various HCV strains
  • • Low resistance risk

Common Side Effects

  • • Nausea
  • • Dizziness
  • • Headache
  • • Digestive issues
  • • Tiredness
  • • Diarrhea

Serious Side Effects

  • • Severe Bradycardia (when taken with amiodarone)
  • • In Hepatitis B co-infections – Hepatitis B flare-ups
  • • Severe liver failure in an advanced stage of liver disorder
  • • Severe drop in red blood count when combined with ribavirin
  • • Depression, mood swings, and confusion

Precautions

To be used cautiously in patients :

  • • Kidney disorders
  • • Liver disorders
  • • Hepatitis B co-infections- cause reactivation
  • • HIV co-infections
  • • When used in combination with ribavirin and amiodarone

Contraindications

  • • Not to be used if any previous allergy or hypersensitivity to Daclatasvir, sofosbuvir, or any excipients
  • • Breastfeeding mothers
  • • Pregnant women

Warning

  • • It is a prescription drug to be taken under medical supervision only.

Important Safety and Monitoring Information

  • • Regular monitoring of hepatic functions, renal functions, cardiac functions, co-infections, and neuropsychiatric adverse reactions.
  • • Drug interactions – Ribavarin and Amiodarone
  • • Not to be used as monotherapy for HCV infections.
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