Sofokast
Sofosbuvir Tablets 400 mg
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Categories: Hepatitis C Medicine Manufacturer, Hepatology
Description
Description
Sofokast
Composition: Sofosbuvir – 400mg
Therapeutic Class: Antivirals
Sofokast: Worldwide Access to Affordable Hepatitis C Medicine
Sofokast, manufactured by Aprazer Healthcare, is a WHO-listed essential medicine for hepatitis C.
Aprazer Healthcare is a globally trusted name in hepatology medicine manufacturing, developing advanced treatments for both hepatitis C and B.
WHO-GMP certified, assuring therapeutic efficacy and safety.
What is Sofokast?
An antiviral against HCV, used in combination for the treatment of Chronic Hepatitis C.
Uses of Sofokast
- • Chronic Hepatitis C
- • HCV-HIV co-infections
How does it work?
It inhibits the viral DNA synthesis, it is a prod rug drug which is activated in the liver.
Benefits
- • Can be used in cirrhosis (compensated /decompensated)
- • HIV co-infections
- • In children> 3 years
- • Post liver transplant
- • Effective across various HCV strains
- • Low resistance risk
Common Side Effects
- • Nausea
- • Dizziness
- • Headache
- • Digestive issues
- • Tiredness
- • Diarrhea
Serious Side Effects
- • Severe Bradycardia (when taken with amiodarone)
- • In Hepatitis B co-infections – Hepatitis B flare-ups
- • Severe liver failure in an advanced stage of liver disorder
- • Severe drop in red blood count when combined with ribavirin
- • Depression, mood swings, and confusion
Precautions
To be used cautiously in patients :
- • Kidney disorders
- • Liver disorders
- • Hepatitis B co-infections- cause reactivation
- • HIV co-infections
- • When used in combination with ribavirin and amiodarone
Contraindications
- • Not to be used if any previous allergy or hypersensitivity to Daclatasvir, sofosbuvir, or any excipients
- • Breastfeeding mothers
- • Pregnant women
Warning
- • It is a prescription drug to be taken under medical supervision only.
Important Safety and Monitoring Information
- • Regular monitoring of hepatic functions, renal functions, cardiac functions, co-infections, and neuropsychiatric adverse reactions.
- • Drug interactions – Ribavarin and Amiodarone
- • Not to be used as monotherapy for HCV infections.
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