Tudobest-L
Tenofovir Disoproxil Fumurate & Lamivudine Tablets IP 300mg/300mg
Tudobest-L
Composition:
Tenofovir – 300mg
Lamivudine-300mg
Classification: HIV medicine
Tudobest: Trusted HIV control
Tudobest is the leading choice worldwide for potent viral suppression, effective against both HIV and hepatitis.
Aprazer Healthcare — Advancing Access to Lifesaving HIV Medicines
Aprazer, the leaders in pharmaceutical drug development, manufactures a range of scientifically backed HIV medicines, affordable and accessible to all.
- • World-class Manufacturing Facility – Lased with advanced technology and precise quality monitoring.
- • Backed with Scientific innovation and continuous R&D for new drug development.
- • International Quality Standards – WHO-GMP certified
- • Affordable and widely prescribed HIV Medicines
- • Trusted in over 50+ countries
What is Tudobest L?
Tudobest is a fixed-dose combination used for the treatment of Hepatitis B and HIV.
Uses of Tudobest L
- • HIV-1 infection
- • Chronic Hepatitis B
How does it work?
It mimics the DNA bases and blocks their multiplication and replication.
Causes chain termination
Cancer cell death
Benefits
- • Potent viral suppression
- • Improves immunity
- • Well tolerated
- • Less frequent dosing
- • Lowers the chances of resistance
- • Prevent disease progression and transmission
Common side effects
- • Nausea
- • Vomiting
- • Diarrhea
- • Skin rashes and ulcers
- • Lightheaded ness
Serious side effects
- • Lactic acidosis
- • Liver damage-yellowish skin, urine, jaundice
- • Kidney damage- urine changes, fluid retention.
- • Stomach pain – inflammation in the pancreas
- • Demineralization of bone- fractures, weakness, pain
- • Severe allergic reaction – breathing difficulty, rash, swelling
Precautions
To be used cautiously in –
- • Reduced renal functions-kidney disorders.
- • Liver disorder
- • Osteoporosis
- • Elderly
- • Pregnant, lactating women
- • Co-infections (Hepatitis B)
- • Metabolic disorders
Important Monitoring Instructions
- • Liver functions
- • Kidney function
- • Bone mineral density
- • Lactic acid levels
- • Viral load and CD4 count
Contraindications
- • Severe liver dysfunction.
- • Hypersensitivity or allergic reaction to the drug or its excipients.
Warnings
To be used under medical prescription.
Do not discontinue abruptly in Hepatitis B patients – may cause serious liver flare-ups
Drug Interactions
- • Anticonvulsant drugs
- • Cardiovascular drugs
- • Antihypertensive
- • Anti-fungal and
- • Anti-tubercular drugs
FAQ
Frequently Asked Questions
Which is the affordable brand for tenofovir disoproxil fumarate/lamivudine tablets?
Tudobest-L, manufactured by Aprazer Healthcare.
Is Tudobest L used in HIV or hepatitis B?
It is used to treat both infections.
Tudobest L (tenofovir disoproxil /lamivudine) is unsafe in advanced kidney disorder?
It is filtered by the kidneys.
It causes kidney injury.
NSAIDs combined with Tudobest L (tenofovir disoproxil /lamivudine). Is it not safe?
It injures the kidney.
Tudobest L affect pancreases. How?
Lamivudine causes inflammation in pancreases.
Avoid leaving Tudobest L abruptly. Why?
It causes reactivation of hepatitis B.
What is the severe effect of Tudobest L (tenofovir disoproxil /lamivudine)?
It can cause
- Lactic acidosis
- Hepatomegaly
