Tudobest-LE

Tudobest LE

Composition:
Tenofovir – 300mg
Efavirenz – 600mg
Lamivudine – 300mg

Classification: HIV medicine

Tudobest LE: Globally Trusted for HIV Control

Tudobest is proven to suppress viral count and boost immunity. It is prescribed worldwide and stands out as an efficient, safe formulation.

Aprazer – Affordable HIV Solutions, Uncompromised Quality

• • Aprazer Healthcare leads the way in HIV drug development, manufactures a range of HIV medicines, including highly effective and widely prescribed, affordable treatments.
• • Manufactures a range of WHO-listed essential HIV medicines.
• • Our portfolio consists of all WHO-listed essential HIV drugs.
• • Cutting-edge manufacturing excellence
• • Continuous R&D – Aprazer continues to develop safe, effective HIV medicines.
• • Scientifically backed formulations
• • Regulatory compliant – WHO-GMP certified, meeting global safety and quality standards.
• • Worldwide reach – available in 50-plus countries
• • Affordable and accessible life-saving medicines.

What is Tudobest LE?

A potent drug combination used once a day for the treatment of HIV infection.

Uses of Tudobest LE

• • HIV infection
• • Prophylaxis of HIV

How does it work?

Inhibits viral DNA replication and multiplication, causing cell death.

Benefits

• • Potent viral suppression
• • Improves immunity
• • Well tolerated
• • Less frequent dosing
• • Lowers the chances of resistance
• • Prevents disease progression and transmission

Common side effects

• • Nausea
• • Vomiting
• • Diarrhea
• • Skin rashes and ulcers
• • Dizziness

Serious side effects

• • Lactic acidosis – buildup of lactic acid in the blood
• • Yellowish skin, urine, jaundice
• • Urine changes, fluid retention, swelling in the legs
• • Inflammation in the pancreas
• • Bone fractures, weakness, and pain in bones
• • Severe allergic reaction – breathing difficulty, rash, swelling

Precautions

To be used cautiously in:

• • Reduced renal functions – kidney disorders
• • Liver disorder
• • Osteoporosis
• • Elderly
• • Pregnant, lactating women
• • Co-infections (Hepatitis B)
• • Metabolic disorders – diabetes, obesity

Important Monitoring Instructions

• • Liver functions – HBV flare-ups
• • Kidney function – creatinine levels
• • Bone mineral density
• • Lactic acid levels in blood
• • Viral load and CD4 count
• • Lipid profile and glucose levels

Contraindications

• • Severe liver dysfunction
• • Hypersensitivity or allergic reaction to the drug or its excipients

Warnings

To be used under medical prescription.

Do not discontinue abruptly in Hepatitis B patients – may cause serious liver flare-ups.

Drug Interactions

• • Anticonvulsant drugs
• • Cardiovascular drugs
• • Antihypertensive
• • Anti-fungal
• • Anti-tubercular drugs