Description
Description
Velakast
Composition: Sofosbuvir 400 mg + Velpatasavir 100 mg
Therapeutic Class: Antiviral
Velakast: Proven Hepatitis C Medicine
Velakast is widely prescribed by doctors worldwide for effective Hepatitis C viral control and elimination.
Aprazer Healthcare: Largest Hepatology Medicine Manufacturer
Aprazer Healthcare is the global exporter and manufacturer of Hepatology medicines.
Reaching the global markets, Aprazer is a renowned brand in hepatology care medicines.
WHO-GMP certified, assured therapeutic efficacy and safety.
What is Velakast?
A potent fixed-dose combination of sofosbuvir and velpatasavir, widely used against all 6 strains of HCV.
Uses of Velakast
- • Chronic Hepatitis C
- • Not to be used as monotherapy for HIV
How does Velakast work?
- • Sofosbuvir inhibits NS5B polymerase
- • Velpatasavir inhibits NS5A polymerase
- • Inhibits viral DNA replication and chain elongation
- • Causes viral cell death
Benefits
- • Reduces viral load
- • Improves liver functions
- • It can be used in both compensated and decompensated liver disease.
- • Effective against all genotypes
- • Short-term therapy
- • Fewer side effects
Common Side Effects
- • Nausea
- • Dizziness
- • Headache
- • Digestive issues
- • Tiredness
- • Diarrhea
Serious Side Effects
- • Irregular heartbeat
- • Trouble breathing
- • Reactivation of Hepatitis B virus (HBV)
Precautions
To be cautiously used in:
- • Cardiac disorders
- • Cirrhosis
- • Use with caution in patients on amiodarone
Contraindications
- • Not to be used if any previous allergy or hypersensitivity to lenvatinib or any excipients
- • Breastfeeding mothers
- • Pregnant women
Warning
- • To be used under medical prescription only
Important Safety and Monitoring Information
- • Regular monitoring of the liver function, renal function, and bone density.
- • Screen for viral load and HIV infections before treatment initiation.
- • Contraception is advised during treatment and for 6 months after if used with ribavirin.
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