Irritable Bowel Syndrome – Symptoms and Drugs
It is a gastrointestinal disorder.
It affects the large intestine.
It causes recurring symptoms.
- Stomach cramps
- Bloating and gas
Changes in bowel habits –
- Diarrhea
- Constipation
What are the symptoms of IBS?
- Abdominal pain /cramps related to poop.
- Excessive gas /bloating
- Diarrhea/constipation
- Mucus in the poop
- Unable to complete vacate the bowel.
Does IBS comprises diarrhea /constipation?
IBS with diarrhea – It is the condition in which watery loose stool is passed.
It consists of frequent urges.
IBS with constipation – It is characterized by hard and dry stools.
The stool is difficult to pass.
Mixed IBS – It is a condition with mixed symptoms.
It is both diarrhea and constipation.
It is an alternating condition between the two.
Irritable bowel syndrome causes –
It is caused by multiple reasons-
- Muscular contractions –
Stronger contractions cause bloating, gas, and abdominal pain.
Weaker contractions cause slower digestion.
It leads to constipation.
- Gut-brain axis – The imbalance in the gut and brain connection. It changes the gut motility.
- Severe infection – Any infection that changes the gut micro biome. It can cause GIT symptoms like diarrhea and constipation.
- Gut–microbiome changes – Changes in the microbiome in the gut also alter gut functioning.
- Visceral hypersensitivity- The weakening of the nerves in the gut. It also leads to sensitivities.
- Food intolerance – Sensitivities /allergies to some foods can also induce IBS.
- Childhood stress – Any severe trauma, stress, sexual or emotional abuse leads to IBS symptoms.
What are the triggers for IBS?
Periods – The drop in hormone levels triggers the release of cytokines.
It induces IBS symptoms.
Stress – It activates the fight-or-flight response.
It makes the gut oversensitive. It disrupts intestinal functions.
Food – sensitivities to food, spicy, oily food can trigger IBS symptoms.
Managing irritable bowel syndrome-
People with IBS must manage their food habits.
- Low dairy or gas-inducing foods.
- Increase fiber in the diet
- Avoid gluten
- Drink plenty of water
Stress management –
Regular sleep, exercise, and other therapies.
What are the medicines used in IBS?
The IBS treatment consists of symptomatic relief –
Constipation drugs – Laxatives, fiber supplements
Anti-diarrheal drugs – They reduce gut motility.
Antibiotics – These are used for gut infections.
Antispasmodic drugs – These are smooth muscle relaxants. It helps relieve painful spasms.
Neuromodulator – These are the low-dose TCAs that calm down the nerve activity.
Why is Aprazer Healthcare chosen by the global drug exporters?
Aprazer Healthcare is a top-tier pharmaceutical manufacturer.
We manufacture global-quality products for worldwide exports.
Our product portfolio comprises a range of essential medicines.
We are the recognised contract pharma manufacturers for –
- NSAID combinations
- Antispasmodic combinations
- Proton Pump Inhibitor & Gastro-resistant drugs
