Chronic Liver Inflammation and the Risk of Liver Cancer
Inflammation that persists in the liver cells for a long time tends to severely damage liver cells and interrupt normal liver functioning.
Acute inflammation exists for a shorter duration, is usually protective. However, chronic inflammation extending longer adversely affects health.
What is chronic liver Inflammation?
The body reacts to foreign stimuli, injury, or infection, causing inflammation.
The inflammation that is left untreated and extends beyond the short duration is called chronic inflammation.
The link between chronic liver Inflammation and liver cancer
- • The inflammation triggers a cascade of events, damaging the cell DNA.
- • Long–term cell injury – the long-term inflammation caused by infections, alcohol, etc., continues to cause liver injury, weaken liver functions, and impair its ability to recover.
- • Immune response overdrive – the chronic inflammation causes the immune system to respond and release signals, causing overactivity, destroying liver tissue and cells.
- • Production of free radicals – the inflammation generates free radicals or oxygen species, which damage cells and cause genetic mutations.
- • Compensatory regeneration – the liver cells over-express themselves to replace the damaged cells. Repetitive cycles of cell division and induced mutations increase the risk of cancer cell multiplication.
- • Liver Fibrosis – damaged or inflamed liver cells form a large tissue scar.
- • Cirrhosis – the fibrosis or tissue scar covers the entire organ. It is an irreversible stage leading to severe liver damage.
- • Cancer development – the series of events, including oxidative stress, immune overactivity, and tissue scarring, causes cancerous transformations.
Causes of Liver cancer – Types of chronic liver inflammation
- • Hepatitis B or C infection – When a virus is not cleared for the long term, it causes an overactive cycle of inflammation.
- • Non Alcoholic Fatty Liver Disease – excessive fat buildup in the liver due to obesity, metabolic disorders, causing liver injury and inflammation, triggering an immune response.
- • Alcoholic Fatty Liver – fat buildup due to alcohol, causing long-term inflammation.
- • Fibrosis – the inflammation that affects tissue, causing tissue scarring.
- • Cirrhosis – the irreversible liver damage or the rebound inflammation.
Final thought to prevent liver cancer
Managing inflammation through timely intervention, lifestyle modification reduces the risk of cancer.
Aprazer Healthcare – Empowering Liver Health, Preventing Cancer
Aprazer, committed to fighting hepatitis globally, manufactures a range of antiviral therapy medicines and hepatoprotective drugs to prevent liver damage.
Aprazer is a world-recognized name and the largest manufacturer of hepatitis B and Hepatitis C medicines.
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