Acalabrutinib Capsules

Acalabrutinib

Classification: Anticancer Medicine

What is Acalabrutinib?

Acalabrutinib is a next-generation drug that is used as targeted therapy treatment for several types of blood cancers.

Uses of Acalabrutinib

It is widely used in adult patients with blood cancer disorders.

• • Chronic Lymphocytic Leukemia
• • Lymphocytic lymphoma
• • Mantle Cell Lymphoma

Acalakast (Acalabrutinib) – Blood Cancer Medicine Trusted Worldwide

Acalakast 100mg (Acalabrutinib ) is widely used to treat blood cancer that cannot be treated by stem cell therapy. It is widely used to treat aggressive Mantle Cell Lymphoma combined with immunotherapy.

Trusted for its quality and safety, Acalakast is widely prescribed owing to its affordability and reliability.

Aprazer Healthcare Making Cancer Treatment Affordable and Accessible

Aprazer Healthcare focuses on developing innovative and complex generic anticancer medicines. Committed to quality and regulatory compliance, Aprazer Healthcare emerged as the leading anticancer medicine manufacturer.

With extensive infrastructure, we have large WHO-GMP, EU-GMP certified manufacturing facilities capable of producing high volumes of oncology orals and injectables. Our extensive product catalogue consists of 30 + anticancer medicines and anticancer injections.

Penetrating the global markets, we are the largest anticancer medicine exporters, supplying worldwide.

Our robust distribution network and supply chain ensure we reach the remotest corners, making the anti-cancer medicines accessible worldwide without geographical barriers.

Working of Acalabrutinib?

It binds to cancer cell proteins and irreversibly inhibits cancer cell division and proliferation. It is highly selective and provides a targeted effect by binding to specific proteins, without affecting other cells.

Common side effects of Acalakast

With specific targeted action and highly selective protein binding, Acalabrutinib shows minimal systemic side effects.

• • Headache
• • Nausea
• • Vomiting
• • Constipation
• • Diarrhea
• • Joint pain
• • Abdominal pain
• • Fatigue

Serious side effects

Acalabrutinib, lowering platelet count increases the risk of bleeding and the risk of opportunistic infections.

Other serious complications include cardiac arrhythmia, leading to pain or discomfort in the chest, and the risk of secondary cancers.

Suddenly stopping the drug may cause Hepatitis B flare in previous Hep-B infections.

Warning using Acalabrutinib

• • Not to be used in patients with prior hypersensitivity to the drug or its excipients.
• • It should be used under a doctor’s advice.
• • Pregnant or breastfeeding women should not use it.

Precautions with Acalabrutinib

To be cautiously used in –

• • Renal insufficient patients
• • Advanced liver disease
• • It causes dizziness; avoid heavy work.

Important Monitoring Considerations

Long–term use of Acalabrutinib may cause cardiac toxicity and bleeding risk. Regular lab tests include blood profile, liver, and cardiac functions.

Storage

Acalabrutinib can be stored at 25-30 degrees temperature and protected from light.

Drug Interactions

The drugs that increase acalabrutinib levels – Antifungals and antibiotics

The drugs that reduce acalabrutinib levels – TB drugs, Antacids, and PPIs.