How Effective is Bosenzer (Bosentan) in Pulmonary Arterial Hypertension?

PAH is the rise of blood pressure in the lungs. A long-term rise in pulmonary BP affects several other organs, including the heart, liver, and kidneys.

Pulmonary Arterial Hypertension?

It is an increase in the blood pressure in the lungs. The pulmonary arteries in the lungs get blocked and obstruct the blood flow. The passage of the blood vessels narrows or gets thinner.

It is the obstructed blood flow to the right side of the heart, affecting the right side at first.

Pulmonary Arterial Hypertension symptoms

• • Shortness of breath
• • Bluish coloration of fingertips or lips
• • Pressure and pain in the chest
• • Weakness
• • Palpitations
• • Dizziness
• • Fluid retention and swelling

What is Idiosyncratic Pulmonary Arterial Hypertension?

The damage to the arterial blood vessels is not caused by a family history or any chronic issue. It is a rare form causing High blood pressure in the lungs due to an unknown cause.

The Causes of Pulmonary Arterial Hypertension

• • Congenital heart disease.
• • Family history of PAH.
• • Respiratory diseases
• • Blood clots in the lungs
• • Immune disorders
• • Severe liver disease
• • Sickle cell anemia
• • Excessive weight
• • Sleep Apnea
• • left side lung disease
• • use of illicit drugs
• • Disorders of the connective tissue
• • Living at height- mountains, hills

Bosenzer (Bosentan) by Aprazer Healthcare

Bosenzer is worldwide available and highly prescribed as an anti-hypertensive treatment for pulmonary arterial hypertension.

• • It improves exercise capacity
• • Slows disease progression
• • Prevent ulcers in the digits – hands and toes
• • Reduces chest pain
• • Improves breathing
• • Improves blood flow to the lungs.

Aprazer Healthcare – Specializes in Specialty Medicines

Aprazer Healthcare is the top global pharmaceutical company, consistently ranking as the world’s largest pharmaceutical manufacturer and exporter. With an extensive product portfolio, we specialize in specialty care medicines, generics, and branded generics. We are committed to high-quality manufacturing supported by WHO-GMP certified manufacturing facilities, stringent quality controls, and regulatory adherence. With global presence and remarkable leadership in pharmaceutical manufacturing, we are the trusted life-saving medicine exporter to 50+ countries.

Working of Bosenzer (Bosentan)

Bosentan is a cholinergic agonist, and it works by blocking endothelin-1, which causes narrowing of the blood vessels. It dilates and relaxes the blood vessels, smoothening the blood flow to the heart.

Common side effects of Bosenzer (Bosentan)

• • Infections of the upper respiratory tract
• • Headache
• • Fluid –retention
• • Low blood count
• • dizziness
• • hypotension
• • joint pain

Precautions and Warnings

Bosenstan can cause severe liver injury and to be avoided in pregnancy due to its teratogenic effects. Effective contraception should be maintained during the course of the treatment, and long-term use may cause a lowering of the sperm count in men.

Conclusion

Bosenzer (Bosenten) is a prescribed medicine and widely used as a primary treatment for pulmonary hypertension.

Bosenzer is available worldwide, and Aprazer Healthcare is the leading Bosentan manufacturer and exporter.