Description
Description
Dasakast -50
Composition – Dasatanib 50mg IP
Therapeutic class: Antineoplastic
Dasakast by Aprazer
As Asia’s largest oncology medicine manufacturer, Aprazer develops affordable, high-quality anticancer medicines, committed to making specialty medicines accessible across the globe.
Our state-of-the-art manufacturing, leveraging cutting-edge technology, manufactures premium quality pharmaceuticals.
- • WHO-GMP certified.
- • Assured safety and therapeutic efficacy.
- • Global reach – exporting to 20+ countries.
Uses of Dasakast
Dasakast is used as a first-line treatment for –
- • Myeloid Leukemia (Chronic)
- • Lymphoblastic leukemia (Acute)
How does Dasakast work?
- • It inhibits various cancer signaling kinase proteins.
- • It inhibits cancer division and growth
Common side effects
- • Fluid retention, oedema
- • Lowering of blood count
- • Nausea
- • Diarrhea
- • Skin ulcers and rashes
Toxicities
- • Bone Marrow suppression – low blood count, RBC, WBC, and Platelets
- • Pleural effusion- shortness of breath, fluid buildup around the lungs
- • Hematological toxicity – bleeding risk, decreased platelet count
- • Hepatotoxicity – elevated enzymes AST and alkaline phosphatase
- • QT Prolongation- irregular heartbeats, strokes
Contraindications
Not to be used in patients-
- • Hypersensitivity or allergic reaction to the drug or its excipients.
- • Breast feeding mothers – it may be passed on to infants or breast feeding children
- • Pregnant women – it may cause teratogenicity.
Precautions
To be cautiously used in patients with –
- • Bleeding disorder
- • Cardiovascular diseases
- • Hepatic, renal impairment
- • Recent surgery or wound
- • Disorders of the stomach
Warnings
Prescription drug to be used under medical supervision.
Important safety and monitoring information
Dasakast requires regular monitoring for hematological functions, blood pressure, liver functions, ECG, regular monitoring of electrolytes.
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