Description
Dasakast 70mg
Composition – Dasatanib 70mg IP
Therapeutic class: Antineoplastic
Dasakast: Fighting Cancer Globally
Aprazer Healthcare, global leaders in oncology care, is at fore forefront in innovation, advanced care treatments, manufacturing high-quality, and global standard anticancer medicines at the state-of-the-art manufacturing facility equipped with cutting-edge technology.
- • WHO-GMP certified.
- • Proven safety and efficacy.
- • Supporting oncology treatment in 20+ countries.
What is Dasakast?
Dasakast is an anticancer medicine used in targeted therapy treatments for blood cancers.
It is used in genetically mutated Philadelphia chromosome-induced leukemia.
Uses of Dasakast
It is used in resistant/intolerant –
- • Chronic Myeloid Leukemia
- • Acute Lymphocytic Lymphoma
How does Dasakast work?
- • It is a tyrosine kinase inhibitor.
- • It blocks abnormal proteins like BCR-ABL.
- • Shrink the tumor and stop the growth of cancer.
Common side effects
- • Low blood count
- • Fluid buildup in the lungs
- • Muscular pain
- • Joint pain
- • Diarrhea
- • Skin rashes
Dose-Dependent Toxicities
- • Bone Marrow Suppression – Bleeding, severely low blood count
- • QT prolongation –irregular heartbeat
- • Fluid retention in lungs
- • Hepatic function impairment –elevated liver enzymes
- • Pulmonary arterial hypertension is a serious side-effect, usually independent of the dose.
Contraindications
Not to be used in patients-
- • Hypersensitivity or allergic reaction to the drug or its excipients.
- • Breastfeeding mothers – it may be passed on to infants or breastfeeding children
- • Pregnant women – it may cause teratogenicity.
Warnings
Prescription drug to be used under medical supervision
Important safety and monitoring information
Dasakast requires regular monitoring for hematological functions, blood pressure, liver functions, ECG, regular monitoring of electrolytes.
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