Description
Description
Lenakast 25mg
Composition: Lenalidomide – 25mg
Therapeutic class: Antineoplastic
Lenakast, engineered to modulate the immune system, is widely accepted and highly prescribed oncologist’s choice of brand for blood cancer.
Aprazer Healthcare: Making Breakthroughs Affordable
- • Aprazer Healthcare, committed to providing affordable healthcare accessible to all, manufactures the highest quality advanced oncology medicines within an affordable range.
- • WHO-GMP certified Medicines
- • Cost-effective range without compromising quality
- • Widely available in developing and emerging markets.
What is Lenakast 25mg?
It is an anticancer drug derived from thalidomide, it has an improved efficacy and safety profile, widely used in various cancers of the blood.
Uses of Lenakast
- • Relapsed /refractory multiple myeloma
- • Relapsed or refractory lymphoma of the mantle cells
- • Bone marrow disorders
How does Lenakast work?
- • Inhibit new blood vessel formation in cancer cells.
- • Enhance the immune activity of T-cells and reduce inflammation.
Common Side Effects
- • Skin rash
- • Thrombosis
- • Tiredness
- • Anemia
- • Indigestion – diarrhea or constipation
Serious Side effects
- • Bone marrow suppression
- • Anemia
- • Gastrointestinal bleeding
- • Hemorrhage
- • Pulmonary embolism
- • Stroke
- • Neuropathy
- • Electrolyte imbalance and kidney failure
- • Skin peeling and severe rash
Contraindications
- • Not to be used if any previous allergy or hypersensitivity to Cytarabine or any excipients.
- • Breastfeeding mothers
- • Pregnant women
Warnings
To be used under the supervision of a medical practitioner or oncology specialist, having adequate diagnostic and monitoring facilities.
Precautions
To be used cautiously in patients with –
- • Impaired kidney function
- • Liver disorders
- • Pre-existing infections
- • Hypertensive patients
- • Elderly patients
- • Cardiovascular disease
- • Immune-compromised individuals
- • Bleeding disorder
- • Autoimmune diseases
Important safety and monitoring information
Monitor creatinine levels
- • LFT and RFT, elevated liver enzymes
- • Thromboembolic events
- • Blood pressure
- • Cardiac functions – ECG/Echo
- • Total blood count
- • Early neuropathy symptoms
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